128315-56-0

128315-56-0 structure

Name: MCH(human, mouse, rat)
Chemical Name: Melanin Concentrating Hormone rat
CAS Number: 128315-56-0
Molecular Formula: C₁₀₅H₁₆₀N₃₀O₂₆S₄
Molecular Weight: 2386.84000
Catalog: Biochemical Peptide
Create Date: 2018-03-27 08:00:00
Modify Date: 2024-01-02 20:11:16
MCH (human, mouse, rat) is a potent peptide agonist of MCH-R and exhibits binding IC50 values of 0.3nM and 1.5 nM for MCH1R and MCH2R, respectively. MCH (human, mouse, rat) is a highly sensitive to MCH-2R in a CHO cell line and monitoring mobilization of intracellular calcium with FLIPR, exhibits functional activation EC50 values of 3.9 nM and 0.1nM for human MCH-1R and MCH-2R, respectively[1].

Name	Melanin Concentrating Hormone rat
Synonyms	MFCD00080193 Melanin Concentrating Hormone,human,mouse Melanin concentrating hormone,human,mouse,rat

Description	MCH (human, mouse, rat) is a potent peptide agonist of MCH-R and exhibits binding IC50 values of 0.3nM and 1.5 nM for MCH1R and MCH2R, respectively. MCH (human, mouse, rat) is a highly sensitive to MCH-2R in a CHO cell line and monitoring mobilization of intracellular calcium with FLIPR, exhibits functional activation EC50 values of 3.9 nM and 0.1nM for human MCH-1R and MCH-2R, respectively[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> MCHR1 (GPR24) Research Areas >> Neurological Disease
Target	Binding IC50: 0.3 nM (MCH1R) IC50: 1.5 nM (MCH1R)[1]
References	[1]. A W Sailer, et al. Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7564-9.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	T+
RIDADR	NONH for all modes of transport
WGK Germany	3