NPEC-caged-(S)-AMPA

Modify Date: 2024-03-09 11:53:07

NPEC-caged-(S)-AMPA Structure
NPEC-caged-(S)-AMPA structure
Common Name NPEC-caged-(S)-AMPA
CAS Number 1257323-84-4 Molecular Weight 379.322
Density 1.5±0.1 g/cm3 Boiling Point 677.7±55.0 °C at 760 mmHg
Molecular Formula C16H17N3O8 Melting Point N/A
MSDS N/A Flash Point 363.7±31.5 °C

 Use of NPEC-caged-(S)-AMPA


NPEC- caged-(S)-AMPA, a caged neurotransmitter analog, is a NPEC photoprotecting group caged the (S)-AMPA (HY-100815A) to make caged ligands specific for glutamate receptor sub-types. NPEC- caged-(S)-AMPA selectively activates AMPA receptor[1].

 Names

Name 3-(5-Methyl-3-oxo-2,3-dihydro-1,2-oxazol-4-yl)-N-{[1-(2-nitrophenyl)ethoxy]carbonyl}-L-alanine
Synonym More Synonyms

 NPEC-caged-(S)-AMPA Biological Activity

Description NPEC- caged-(S)-AMPA, a caged neurotransmitter analog, is a NPEC photoprotecting group caged the (S)-AMPA (HY-100815A) to make caged ligands specific for glutamate receptor sub-types. NPEC- caged-(S)-AMPA selectively activates AMPA receptor[1].
Related Catalog
Target

AMPA Receptor

References

[1]. Francisco Palma-Cerda, et al. New caged neurotransmitter analogs selective for glutamate receptor sub-types based on methoxynitroindoline and nitrophenylethoxycarbonyl caging groups. Neuropharmacology. 2012 Sep;63(4):624-34.  

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 677.7±55.0 °C at 760 mmHg
Molecular Formula C16H17N3O8
Molecular Weight 379.322
Flash Point 363.7±31.5 °C
Exact Mass 379.101563
LogP 2.10
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.605

 Synonyms

3-(5-Methyl-3-oxo-2,3-dihydro-1,2-oxazol-4-yl)-N-{[1-(2-nitrophenyl)ethoxy]carbonyl}-L-alanine
4-Isoxazolepropanoic acid, 2,3-dihydro-5-methyl-α-[[[1-(2-nitrophenyl)ethoxy]carbonyl]amino]-3-oxo-, (αS)-