EGFR-IN-9
Modify Date: 2025-08-27 12:47:17
EGFR-IN-9 structure
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Common Name | EGFR-IN-9 | ||
|---|---|---|---|---|
| CAS Number | 1226549-39-8 | Molecular Weight | 476.53 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H24N4O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of EGFR-IN-9EGFR-IN-9 (Compound 8) is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M). EGFR-IN-9 has antitumor activity[1]. |
| Name | EGFR-IN-9 |
|---|
| Description | EGFR-IN-9 (Compound 8) is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M). EGFR-IN-9 has antitumor activity[1]. |
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| Related Catalog | |
| Target |
EGFR (WT):7 nM (IC50) EGFRL858R/T790M:28 nM (IC50) |
| In Vitro | EGFR-IN-9 (Compound 8) shows antiproliferative activity in HCC827 lung cancer cell line with an IC50 of 8 nM. |
| References |
| Molecular Formula | C29H24N4O3 |
|---|---|
| Molecular Weight | 476.53 |