1226549-39-8
1226549-39-8 structure
- Name: EGFR-IN-9
- Chemical Name: EGFR-IN-9
- CAS Number: 1226549-39-8
- Molecular Formula: C29H24N4O3
- Molecular Weight: 476.53
- Catalog: Signaling Pathways JAK/STAT Signaling EGFR
- Create Date: 2019-12-07 15:40:59
- Modify Date: 2024-01-05 23:12:07
-
EGFR-IN-9 (Compound 8) is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M). EGFR-IN-9 has antitumor activity[1].
| Name | EGFR-IN-9 |
|---|
| Description | EGFR-IN-9 (Compound 8) is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M). EGFR-IN-9 has antitumor activity[1]. |
|---|---|
| Related Catalog | |
| Target |
EGFR (WT):7 nM (IC50) EGFRL858R/T790M:28 nM (IC50) |
| In Vitro | EGFR-IN-9 (Compound 8) shows antiproliferative activity in HCC827 lung cancer cell line with an IC50 of 8 nM. |
| References |
| Molecular Formula | C29H24N4O3 |
|---|---|
| Molecular Weight | 476.53 |