Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

2416924-99-5

2416924-99-5 structure

2416924-99-5 structure

Name: EGFR-IN-67
Chemical Name: EGFR-IN-67
CAS Number: 2416924-99-5
Molecular Formula: C₁₈H₁₇N₃S
Molecular Weight: 307.41
Catalog: Signaling Pathways JAK/STAT Signaling EGFR
Create Date: 2022-08-06 17:57:04
Modify Date: 2025-08-26 23:53:00
EGFR-IN-67 (Compound 7d) is a potent EGFR inhibitor with an IC50 of 0.34 μM. EGFR-IN-67 shows anticancer activity[1].

Name	EGFR-IN-67

Description	EGFR-IN-67 (Compound 7d) is a potent EGFR inhibitor with an IC50 of 0.34 μM. EGFR-IN-67 shows anticancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
Target	EGFR:0.34 μM (IC50)
In Vitro	EGFR-IN-67 (Compound 7d) shows cytotoxicity with IC50 values of 4.53 ± 0.28 μM and 39.10 ± 2.37 μM against MCF-7 and WI-38, respectively[1].
References	[1]. George RF, et al. Some 1,3,5-trisubstituted pyrazoline derivatives targeting breast cancer: Design, synthesis, cytotoxic activity, EGFR inhibition and molecular docking. Bioorg Chem. 2020 Jun;99:103780.

Molecular Formula	C₁₈H₁₇N₃S
Molecular Weight	307.41

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.