EGFR-IN-28 structure
|
Common Name | EGFR-IN-28 | ||
|---|---|---|---|---|
| CAS Number | 2754392-31-7 | Molecular Weight | 711.68 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C31H39BrN10O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of EGFR-IN-28EGFR-IN-28 is a potent EGFR inhibitor. EGFR-IN-28 has antitumor activity[1]. |
| Name | EGFR-IN-28 |
|---|
| Description | EGFR-IN-28 is a potent EGFR inhibitor. EGFR-IN-28 has antitumor activity[1]. |
|---|---|
| Related Catalog | |
| Target |
EGFR |
| In Vitro | EGFR-IN-28 inhibits Δ19Del, L858R, Δ19Del/T790M, L858R/T790M, Δ19Del/T790M/C797S, L858R/T790M/C797S (all IC50s≤50nM)[1]. |
| References |
[1]. Xianming Deng, et al. EGFR inhibitor, preparation method and application thereof. WO2021238827A1. |
| Molecular Formula | C31H39BrN10O3S |
|---|---|
| Molecular Weight | 711.68 |
| InChIKey | HFECFFOTIRJWCG-UHFFFAOYSA-N |
| SMILES | COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2N(C)S(C)(=O)=O)n1 |