EGFR-IN-25

Modify Date: 2025-08-26 17:02:34

EGFR-IN-25 Structure
EGFR-IN-25 structure
Common Name EGFR-IN-25
CAS Number 2749562-63-6 Molecular Weight 609.76
Density N/A Boiling Point N/A
Molecular Formula C34H43N9O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of EGFR-IN-25


EGFR-IN-25 is a potent EGFR inhibitor with IC50s of 9 nM and 60 nM for BaF3 cells (EGFR DEL19/T790M/C797S) and A431 cells (WT), respectively[1].

 Names

Name EGFR-IN-25

 EGFR-IN-25 Biological Activity

Description EGFR-IN-25 is a potent EGFR inhibitor with IC50s of 9 nM and 60 nM for BaF3 cells (EGFR DEL19/T790M/C797S) and A431 cells (WT), respectively[1].
Related Catalog
References

[1]. New pyrazine compound. WO2021244505A1.

 Chemical & Physical Properties

Molecular Formula C34H43N9O2
Molecular Weight 609.76
InChIKey ZNERTSDRRJRWIJ-UHFFFAOYSA-N
SMILES CN1CCN(C2CCN(c3ccc(Nc4nc(NC5CCOCC5)c(-c5cccc6[nH]ccc56)nc4C(N)=O)cc3)CC2)CC1
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