EGFR-IN-22

Modify Date: 2024-01-09 21:01:25

EGFR-IN-22 Structure
EGFR-IN-22 structure
Common Name EGFR-IN-22
CAS Number 2634646-14-1 Molecular Weight 805.72
Density N/A Boiling Point N/A
Molecular Formula C38H47BrFN10O2P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of EGFR-IN-22


EGFR-IN-22 is a potent EGFR inhibitor with IC50s of 4.91 nM and 0.54 nM for wild type EGFR and EGFRL858R/T790M/C797S, respectively (CN112538072A, compound 243)[1].

 Names

Name EGFR-IN-22

 EGFR-IN-22 Biological Activity

Description EGFR-IN-22 is a potent EGFR inhibitor with IC50s of 4.91 nM and 0.54 nM for wild type EGFR and EGFRL858R/T790M/C797S, respectively (CN112538072A, compound 243)[1].
Related Catalog
Target

EGFRL858R/T790M/C797S:0.54 nM (IC50)

EGFR (WT):4.91 nM (IC50)

References

[1]. EGFR-IN-22 is a potent EGFR inhibitor with IC50 of 4.91 nM and 0.54 nM for wild type EGFR and EGFRL858R/T790M/C797S, respectively (CN112538072A, compound 243)[1].

 Chemical & Physical Properties

Molecular Formula C38H47BrFN10O2P
Molecular Weight 805.72