EGFR-IN-64

Modify Date: 2025-08-27 14:32:30

EGFR-IN-64 Structure
EGFR-IN-64 structure
Common Name EGFR-IN-64
CAS Number 2416924-93-9 Molecular Weight 351.40
Density N/A Boiling Point N/A
Molecular Formula C20H21N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of EGFR-IN-64


EGFR-IN-64 (Compound 3c) is a potent EGFR inhibitor with an IC50 of 0.33 μM. EGFR-IN-64 shows anticancer activity[1].

 Names

Name EGFR-IN-64

 EGFR-IN-64 Biological Activity

Description EGFR-IN-64 (Compound 3c) is a potent EGFR inhibitor with an IC50 of 0.33 μM. EGFR-IN-64 shows anticancer activity[1].
Related Catalog
Target

EGFR:0.33 μM (IC50)

In Vitro EGFR-IN-64 (Compound 3c) shows cytotoxicity with IC50 values of 4.46 ± 0.11 μM and 16.23 ± 0.65 μM against MCF-7 and WI-38, respectively[1].
References

[1]. George RF, et al. Some 1,3,5-trisubstituted pyrazoline derivatives targeting breast cancer: Design, synthesis, cytotoxic activity, EGFR inhibition and molecular docking. Bioorg Chem. 2020 Jun;99:103780.

 Chemical & Physical Properties

Molecular Formula C20H21N3O3
Molecular Weight 351.40
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