2752328-62-2
2752328-62-2 structure
- Name: EGFR-IN-27
- Chemical Name: EGFR-IN-27
- CAS Number: 2752328-62-2
- Molecular Formula: C35H46N9O2P
- Molecular Weight: 655.77
- Catalog: Signaling Pathways JAK/STAT Signaling EGFR
- Create Date: 2022-04-25 20:41:19
- Modify Date: 2024-01-13 18:41:32
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EGFR-IN-27 is a potent EGFR inhibitor with IC50s of <50 nM for EGFR Del, L858R, Del/T790M, L858R/T790M, Del/T790M/C797S, and L858R/T790M/C797S, respectively (WO2021249324A1, compound 511)[1].
| Name | EGFR-IN-27 |
|---|
| Description | EGFR-IN-27 is a potent EGFR inhibitor with IC50s of <50 nM for EGFR Del, L858R, Del/T790M, L858R/T790M, Del/T790M/C797S, and L858R/T790M/C797S, respectively (WO2021249324A1, compound 511)[1]. |
|---|---|
| Related Catalog | |
| Target |
EGFRdel19:<50 nM (IC50) EGFRL858R:<50 nM (IC50) EGFRL858R/T790M:<50 nM (IC50) EGFRdel19 T790M C797S:<50 nM (IC50) EGFR (C797S/T790M/L858R):<50 nM (IC50) EGFRdel19 T790M:<50 nM (IC50) |
| References |
[1]. Alkenyl pyrimidine compound, preparation method therefor, and application thereof. WO2021249324A1. |
| Molecular Formula | C35H46N9O2P |
|---|---|
| Molecular Weight | 655.77 |