EGFR-IN-5

Modify Date: 2023-01-23 21:55:25

EGFR-IN-5 Structure
EGFR-IN-5 structure
 Common Name EGFR-IN-5
CAS Number 2225887-26-1 Molecular Weight 571.69
Density N/A Boiling Point N/A
Molecular Formula C31H38FN9O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of EGFR-IN-5


EGFR-IN-5 is a EGFR inhibitor with IC50s of 10.4, 1.1, 34, 7.2 nM for EGFR, EGFRL858R, EGFRL858R/T790M, and EGFRL858R/T790M/C797S, respectively.

 Names

Name EGFR-IN-5
Synonym More Synonyms

 EGFR-IN-5 Biological Activity

Description EGFR-IN-5 is a EGFR inhibitor with IC50s of 10.4, 1.1, 34, 7.2 nM for EGFR, EGFRL858R, EGFRL858R/T790M, and EGFRL858R/T790M/C797S, respectively.
Related Catalog
Target

EGFR:10.4 nM (IC50)

EGFRL858R:1.1 nM (IC50)

EGFRL858R/T790M:34 nM (IC50)

EGFRL858R/T790M/C797S:7.2 nM (IC50)
References

[1]. Zhang H, et al. Discovery of 2,4,6-trisubstitued pyrido[3,4-d]pyrimidine derivatives as new EGFR-TKIs. Eur J Med Chem. 2018 Mar 25;148:221-237.

 Chemical & Physical Properties

Molecular Formula C31H38FN9O
Molecular Weight 571.69

 Synonyms

MFCD31813637
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Related Compounds: More...
EGFR-IN-59
2529891-44-7
EGFR-IN-53
2418549-33-2
EGFR-IN-54
2418549-30-9
EGFR-IN-51
2418549-32-1
EGFR-IN-52
454436-75-0
EGFR-IN-57
2492382-37-1
EGFR-IN-55
2057423-46-6
EGFR-IN-56
2477726-83-1
EGFR-IN-50
2044508-48-5
Chemsrc provides EGFR-IN-5(CAS#:2225887-26-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of EGFR-IN-5 are included as well.>> amp version: EGFR-IN-5

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