Renin inhibitor-1 structure
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Common Name | Renin inhibitor-1 | ||
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CAS Number | 1093082-54-2 | Molecular Weight | 414.50 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C22H30N4O4 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Renin inhibitor-1Renin inhibitor-1 (compound 26) is a potent and orally active renin inhibitor with IC50s of 0.9, 1.8 nM for rh-renin and hPRA, respectively. Renin inhibitor-1 shows antihypertensive efficacy. Renin inhibitor-1 has the potential for the research of hypertension and cardiovascular/renal diseases[1]. |
Name | Renin inhibitor-1 |
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Description | Renin inhibitor-1 (compound 26) is a potent and orally active renin inhibitor with IC50s of 0.9, 1.8 nM for rh-renin and hPRA, respectively. Renin inhibitor-1 shows antihypertensive efficacy. Renin inhibitor-1 has the potential for the research of hypertension and cardiovascular/renal diseases[1]. |
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Related Catalog | |
Target |
IC50: 0.9 nM (rh-renin); 1.8 nM (hPRA)[1] |
In Vivo | Renin inhibitor-1 (compound 26) (10 mg/kg; p.o.) demonstrates a significantly potent hypotensive effect in tsukuba hypertensive mice[1]. |
References |
Molecular Formula | C22H30N4O4 |
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Molecular Weight | 414.50 |