[Pro9]-Substance P

Modify Date: 2025-08-20 16:32:28

[Pro9]-Substance P Structure
[Pro9]-Substance P structure
Common Name [Pro9]-Substance P
CAS Number 104486-69-3 Molecular Weight 1387.69000
Density 1.43g/cm3 Boiling Point N/A
Molecular Formula C66H102N18O13S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of [Pro9]-Substance P


[Pro9]-Substance P is a potent, reversible and selective agonist of NK-1 tachykinin receptors with an EC50 of 0.93 nM[1].

 Names

Name arg-pro-lys-pro-gln-gln-phe-phe-pro-leu-met-nh2
Synonym More Synonyms

 [Pro9]-Substance P Biological Activity

Description [Pro9]-Substance P is a potent, reversible and selective agonist of NK-1 tachykinin receptors with an EC50 of 0.93 nM[1].
Related Catalog
Target

NK1:0.93 nM (EC50)

In Vitro [3H][Pro9]-Substance P can be used as a radio ligand for NK- 1 binding sites[1]. [Pro9]-Substance P stimulates inositol phosphate formation with an efficacy only slightly lower than that of SP (EC50 values of 0.93 ± 0.07 and 0.45 ± 0.06 nM, respectively) on primary cultures of newborn mouse cortical glial cells[1].

 Chemical & Physical Properties

Density 1.43g/cm3
Molecular Formula C66H102N18O13S
Molecular Weight 1387.69000
Exact Mass 1386.76000
PSA 533.14000
LogP 4.61590
Index of Refraction 1.669

 Safety Information

WGK Germany 3

 Synonyms

H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Pro-Leu-Met-NH2
9-L-PROLINE-SUBSTANCE P
substance P,Pro(9)
RPKPQQFFPLM-NH2
[TYR9]-SUBSTANCE P
[Pro9]SP
[PRO9] SUBSTANCE P
L-Arg-L-Pro-L-Lys-L-Pro-L-Gln-L-Gln-L-Phe-L-Phe-L-Pro-L-Leu-L-Met-NH2
pro(9)-substance
[Pro9]-Substance P
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