(D-Ala4)-Substance P (4-11)

Modify Date: 2025-08-26 22:29:46

(D-Ala4)-Substance P (4-11) Structure
(D-Ala4)-Substance P (4-11) structure
 Common Name (D-Ala4)-Substance P (4-11)
CAS Number 81381-50-2 Molecular Weight 940.120
Density 1.3±0.1 g/cm3 Boiling Point 1450.5±65.0 °C at 760 mmHg
Molecular Formula C44H65N11O10S Melting Point N/A
MSDS N/A Flash Point 831.0±34.3 °C

 Use of (D-Ala4)-Substance P (4-11)


[DAla4] Substance P (4-11) is an analog of Substance P (Substance P (HY-P0201)) that inhibits the binding of 125I-Bolton Hunter-conjugated Eledoisin (Eledoisin (HY-P0006)) (IC50 of 0.5 μM) and 125I-Bolton Hunter-conjugated Substance P (IC50 of 0.15 μM) to rat brain cortex membranes[1].

 Names

Name [D-Ala4]-Substance P (4-11)
Synonym More Synonyms

 (D-Ala4)-Substance P (4-11) Biological Activity

Description [DAla4] Substance P (4-11) is an analog of Substance P (Substance P (HY-P0201)) that inhibits the binding of 125I-Bolton Hunter-conjugated Eledoisin (Eledoisin (HY-P0006)) (IC50 of 0.5 μM) and 125I-Bolton Hunter-conjugated Substance P (IC50 of 0.15 μM) to rat brain cortex membranes[1].
Related Catalog
In Vitro Eledoisin 和 Substance P 是速激肽的一类肽成员，它们具有相似的生物活性谱。[DAla4] Substance P (4-11) ([D-Ala0-(5-11)]SP) 抑制 125I-Bolton Hunter-conjugated 偶联的 Eledoisin 和 125I-Bolton Hunter 偶联的 Substance P 与大鼠大脑皮层膜的结合[1]。
References

[1]. M A Cascieri, et al. Demonstration of two distinct tachykinin receptors in rat brain cortex. J Biol Chem. 1985 Feb 10;260(3):1501-7.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 1450.5±65.0 °C at 760 mmHg
Molecular Formula C44H65N11O10S
Molecular Weight 940.120
Flash Point 831.0±34.3 °C
Exact Mass 939.463684
PSA 384.29000
LogP 0.37
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.578

 Synonyms

D-Alanyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-L-methioninamide
Substance P,fragment 4-11,(D-Ala4)
D-ALA-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2
H-D-ALA-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2
L-Methioninamide, D-alanyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-
SUBSTANCE P OCTAPEPTIDE D-ALA-4-FRAGMENT 4-11)
(D-ALA4)-SUBSTANCE P (4-11)
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Chemsrc provides (D-Ala4)-Substance P (4-11)(CAS#:81381-50-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of (D-Ala4)-Substance P (4-11) are included as well.>> amp version: (D-Ala4)-Substance P (4-11)

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