Hypoxanthine
Names
[ CAS No. ]:
68-94-0
[ Name ]:
Hypoxanthine
[Synonym ]:
3,9-Dihydro-6H-purin-6-on
1,7-Dihydro-6H-purin-6-on
6-Oxopurine
1,7-Dihydro-6H-purin-6-one
7H-Purin-6-ol
PURIN-6-OL
Hypexanthine
SARKIN
SARCINE
Hypoxathine
3,9-Dihydro-6H-purin-6-one
MFCD00005725
Hypoxanthine
Purine-6-ol
6-oxypurine
Sarkine
Hypoxanthin
6-Hydroxypurine
EINECS 200-697-3
1H,7H-Hypoxanthine
1,7-dihydro-purin-6-one
1,7-Dihydro-6H-purine-6-one
Biological Activity
[Description]:
[Related Catalog]:
[Target]
Human Endogenous Metabolite
[In Vitro]
[In Vivo]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.7±0.1 g/cm3
[ Boiling Point ]:
551.0±30.0 °C at 760 mmHg
[ Melting Point ]:
>300 °C(lit.)
[ Molecular Formula ]:
C5H4N4O
[ Molecular Weight ]:
136.111
[ Flash Point ]:
287.0±24.6 °C
[ Exact Mass ]:
136.038513
[ PSA ]:
74.43000
[ LogP ]:
-0.91
[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C
[ Index of Refraction ]:
1.816
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
practically insoluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UP0791000
- CHEMICAL NAME :
- 6H-Purin-6-one, 1,7-dihydro-
- CAS REGISTRY NUMBER :
- 68-94-0
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C5-H4-N4-O
- MOLECULAR WEIGHT :
- 136.13
- WISWESSER LINE NOTATION :
- T56 BN DM FVM INJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 600 mg/kg
- SEX/DURATION :
- female 13 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - fetal death
- REFERENCE :
- JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc., c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto 606, Japan) V.1- 1951- Volume(issue)/page/year: 22,201,1972
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 1 gm/kg
- SEX/DURATION :
- female 13 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- REFERENCE :
- JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc., c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto 606, Japan) V.1- 1951- Volume(issue)/page/year: 22,201,1972 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6051 No. of Facilities: 64 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 541 (estimated) No. of Female Employees: 355 (estimated)
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S22-S24/25-S37/39-S26
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
UP0791000
[ HS Code ]:
2933990090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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