Triethyl orthoformate

Names

[ CAS No. ]:
122-51-0

[ Name ]:
Triethyl orthoformate

[Synonym ]:
1,1,1-Triethoxymethane
triethoxymethane
EINECS 204-550-4
Ethyl orthoformate
UNII:355LRR361Q
Orthopropionic Acid Triethyl Ester
Orthoformic acid, triethyl ester
4-02-00-00025 (Beilstein Handbook Reference)
ortho-formic acid triethyl ester
(Diethoxymethoxy)ethane
Formylolate
MFCD00009230
1,1,1-Triethoxypropane
ethyl-orthoformate
triethyl ortho formate
Triethyl orthoformate
Orthoformic acid triethyl ester
ETHYL-O-FORMATE
Ethyl orthoformate [UN2524] [Flammable liquid]
1,1',1''-[methanetriyltris(oxy)]triethane
AETHON
ETHONE
triethylorthoformate
TEOF
Triethoxmethane
Ethyl Orthopropionate
Methane, triethoxy-
triethoxy-methan
Triethyl Orthopropionate
Propane, 1,1,1-triethoxy-
Ethane, 1,1',1''-[methylidynetris(oxy)]tris-
ortho-formic

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
142.5±0.0 °C at 760 mmHg

[ Melting Point ]:
−76 °C(lit.)

[ Molecular Formula ]:
C₇H₁₆O₃

[ Molecular Weight ]:
148.200

[ Flash Point ]:
30.0±0.0 °C

[ Exact Mass ]:
148.109940

[ PSA ]:
27.69000

[ LogP ]:
2.14

[ Vapour density ]:
5.11 (vs air)

[ Vapour Pressure ]:
7.0±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.400

[ Water Solubility ]:
1.35 g/L

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RM6475000

CHEMICAL NAME :: Orthoformic acid, triethyl ester

CAS REGISTRY NUMBER :: 122-51-0

BEILSTEIN REFERENCE NO. :: 0605384

LAST UPDATED :: 199806

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C7-H16-O3

MOLECULAR WEIGHT :: 148.23

WISWESSER LINE NOTATION :: 2OYO2&O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,352,1986

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,352,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7060 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,119,1951

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4000 ppm/8H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,119,1951

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 20 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,119,1951

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: >10 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,917,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84005 No. of Facilities: 5 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 20 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84005 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1582 (estimated) No. of Female Employees: 323 (estimated)

Safety Information

[ Symbol ]:

GHS02

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226

[ Precautionary Statements ]:
P210-P403 + P235

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R10;R36/38

[ Safety Phrases ]:
S16-S26-S37/39

[ RIDADR ]:
UN 2524 3/PG 3

[ WGK Germany ]:
1

[ RTECS ]:
RM6475000

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
2915130000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2909199090

[ Summary ]:
2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

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