2-Aminoisobutyric acid

Names

[ CAS No. ]:
62-57-7

[ Name ]:
2-Aminoisobutyric acid

[Synonym ]:
a-Methylalanine
α-Methylalanine
2-amino-2-methylpropanoic acid
2-Aminoisobutyricacid
α-Aminoisobutyric acid
Alanine, 2-methyl-
2-Ammonio-2-methylpropanoate
EINECS 200-544-0
(α-methyl)alanine
a-Aminoisobutyric acid
2-Amino-2-methylpropionic acid
a-Aminoisobutanoic acid
2-methyl-2-aminopropanoic acid
2-Amino-2-MethylpropionicAcid
2-Aminoisobutyric Acid
Aib
MFCD00008049
NSC 16590

Biological Activity

[Description]:

NSC 16590 inhibits the production of endogenous ethylene in the cotyledonary segments of cocklebur.

[Related Catalog]:

Research Areas >> Others

Natural Products >> Others

[Target]

Human Endogenous Metabolite

[In Vitro]

NSC 16590 (α-Aminoisobutyric acid , AIB) inhibits the production of endogenous ethylene in the cotyledonary segments of cocklebur (Xanthium pennsylvanicum Wallr.) seeds most strongly. NSC 16590 at 4 mM inhibits the formation of ethylene by about 50%, although the O2 uptake of the segments is not affected even at 20 mM. NSC 16590 also inhibits ethylene formation in the stem segments of etiolated pea (Pisum satiuum L. cv. Alaska) seedlings. Kinetic analysis with cell free extracts from etiolated pea shoots reveals that NSC 16590 competitively inhibits the conversion of ACC into ethylene[1].

[References]

[1]. Shigeru Satoh, et al. α-Aminoisobutyric acid: A probable competitive inhibitor of conversion of 1-aminocyclopropane-1-carboxylic acid to ethylene. Plant and Cell Physiology, Volume 21, Issue 6, 1 September 1980, Pages 939-949.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
204.4±23.0 °C at 760 mmHg

[ Melting Point ]:
≥300 °C

[ Molecular Formula ]:
C₄H₉NO₂

[ Molecular Weight ]:
103.120

[ Flash Point ]:
77.4±22.6 °C

[ Exact Mass ]:
103.063332

[ PSA ]:
63.32000

[ LogP ]:
-0.33

[ Vapour Pressure ]:
0.1±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.464

[ Storage condition ]:
Store at RT.

[ Water Solubility ]:
SOLUBLE

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AY7000000

CHEMICAL NAME :: Alanine, 2-methyl-

CAS REGISTRY NUMBER :: 62-57-7

BEILSTEIN REFERENCE NO. :: 0506496

LAST UPDATED :: 199706

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C4-H9-N-O2

MOLECULAR WEIGHT :: 103.14

WISWESSER LINE NOTATION :: ZX1&1&VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 5,108,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 750 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
C

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
AY7000000

[ HS Code ]:
29224995

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

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