Boc-Aib-OH

Names

[ Name ]:
Boc-Aib-OH

[Synonym ]:
N-Boc-2-Aminoisobutanoic acid
Boc-Aib-OH
2-(1,1-dimethylethoxycarbonyl)amino-2-methyl-propionic acid
BOC-α-Methylalanine
N-((1,1-Dimethylethoxy)carbonyl)-2-methyl-alanine
Aspartic acid, 2-methyl-, 4-(1,1-dimethylethyl) ester
N-Boc-2-methylalanine
2-Amino-2-methyl-4-[(2-methyl-2-propanyl)oxy]-4-oxobutanoic acid
2-(tert-butoxycarbonyl)amino-2-methylpropanoic acid
α-(Boc-amino)isobutyric acid
2-(tert-Butoxycarbonylamino)isobutyric Acid
N-(tert-butoxycarbonyl)-2-aminoisobutyric acid
2-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}alanine
Boc-Alpha-Methylalanine
Alanine, N-[(1,1-dimethylethoxy)carbonyl]-2-methyl-
2-tert-butoxycarbonylamino-2-methyl-propionic acid
Boc-2-aminoisobutyric acid
N-Boc-2-amino-2-methylpropanoic acid
2-((tert-Butoxycarbonyl)amino)-2-methylpropanoic acid
2-[(1,1-dimethylethoxy)carbonyl]amino-2-methyl-propanoic acid
N-Boc-α-methylalanine
2-(Boc-amino)isobutyric Acid
N-Boc-2-aminoisobutyric acid
N-(tert-butoxycarbonyl)-2-methylalanine
EINECS 250-421-0
MFCD00042973

Biological Activity

[Description]:

2-((tert-Butoxycarbonyl)amino)-2-methylpropanoic acid is an alanine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1105.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
325.6±37.0 °C at 760 mmHg

[ Melting Point ]:
118-122 °C

[ Molecular Formula ]:
C₉H₁₇NO₄

[ Molecular Weight ]:
203.236

[ Flash Point ]:
150.7±26.5 °C

[ Exact Mass ]:
203.115753

[ PSA ]:
75.63000

[ LogP ]:
1.29

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.477

[ Storage condition ]:
0-6°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Unraveling the interplay of backbone rigidity and electron rich side-chains on electron transfer in peptides: the realization of tunable molecular wires.

J. Am. Chem. Soc. 136(35) , 12479-88, (2014)

Electrochemical studies are reported on a series of peptides constrained into either a 310-helix (1-6) or β-strand (7-9) conformation, with variable numbers of electron rich alkene containing side cha...

W. Mayr, G. Jung

Liebigs Ann. Chem. (and reference cited therein) , 715, (1980)