GL Biochem (Shanghai) Ltd.
China
Product Name: 2-Aminoisobutyric acid
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 2-Aminoisobutyric acid
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Nanjing Peptide Biotech Ltd
China
Product Name: H-Aib-OH
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Dayang Chem (Hangzhou) Co., Ltd.
China
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Zhejiang Hangyu API Co., Ltd
China
Product Name: 2-Aminoisobutyric acid
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Purity: 99.5%
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62-57-7

62-57-7 structure

62-57-7 structure

Name: 2-Aminoisobutyric acid
Chemical Name: 2-Aminoisobutyric acid
CAS Number: 62-57-7
Molecular Formula: C₄H₉NO₂
Molecular Weight: 103.120
Catalog: Biochemical Amino acids and their derivatives Alanine derivatives
Create Date: 2018-03-23 08:00:00
Modify Date: 2024-01-02 15:54:00
NSC 16590 inhibits the production of endogenous ethylene in the cotyledonary segments of cocklebur.

Name	2-Aminoisobutyric acid
Synonyms	a-Methylalanine α-Methylalanine 2-amino-2-methylpropanoic acid 2-Aminoisobutyricacid α-Aminoisobutyric acid Alanine, 2-methyl- 2-Ammonio-2-methylpropanoate EINECS 200-544-0 (α-methyl)alanine a-Aminoisobutyric acid 2-Amino-2-methylpropionic acid a-Aminoisobutanoic acid 2-methyl-2-aminopropanoic acid 2-Amino-2-MethylpropionicAcid 2-Aminoisobutyric Acid Aib MFCD00008049 NSC 16590

Description	NSC 16590 inhibits the production of endogenous ethylene in the cotyledonary segments of cocklebur.
Related Catalog	Research Areas >> Others Natural Products >> Others
Target	Human Endogenous Metabolite
In Vitro	NSC 16590 (α-Aminoisobutyric acid , AIB) inhibits the production of endogenous ethylene in the cotyledonary segments of cocklebur (Xanthium pennsylvanicum Wallr.) seeds most strongly. NSC 16590 at 4 mM inhibits the formation of ethylene by about 50%, although the O2 uptake of the segments is not affected even at 20 mM. NSC 16590 also inhibits ethylene formation in the stem segments of etiolated pea (Pisum satiuum L. cv. Alaska) seedlings. Kinetic analysis with cell free extracts from etiolated pea shoots reveals that NSC 16590 competitively inhibits the conversion of ACC into ethylene[1].
References	[1]. Shigeru Satoh, et al. α-Aminoisobutyric acid: A probable competitive inhibitor of conversion of 1-aminocyclopropane-1-carboxylic acid to ethylene. Plant and Cell Physiology, Volume 21, Issue 6, 1 September 1980, Pages 939-949.

Density	1.1±0.1 g/cm3
Boiling Point	204.4±23.0 °C at 760 mmHg
Melting Point	≥300 °C
Molecular Formula	C₄H₉NO₂
Molecular Weight	103.120
Flash Point	77.4±22.6 °C
Exact Mass	103.063332
PSA	63.32000
LogP	-0.33
Vapour Pressure	0.1±0.8 mmHg at 25°C
Index of Refraction	1.464
Storage condition	Store at RT.
Water Solubility	SOLUBLE

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AY7000000

CHEMICAL NAME :: Alanine, 2-methyl-

CAS REGISTRY NUMBER :: 62-57-7

BEILSTEIN REFERENCE NO. :: 0506496

LAST UPDATED :: 199706

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C4-H9-N-O2

MOLECULAR WEIGHT :: 103.14

WISWESSER LINE NOTATION :: ZX1&1&VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 5,108,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 750 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	C
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	AY7000000
HS Code	29224995

Precursor 7
444574-99-6 13257-67-5 77-71-4 143-33-9
67-64-1 57224-51-8 1236074-96-6
DownStream 10
1113-49-1 106556-63-2 4512-32-7 94744-50-0
220022-94-6 594-61-6 75-31-0 29513-50-6
2707-93-9 2654-97-9

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%