2-Guanidinoacetic acid

Names

[ CAS No. ]:
352-97-6

[ Name ]:
2-Guanidinoacetic acid

[Synonym ]:
Guanidinoacetic acid
Acide carbamimidamidoacétique
Guanyl glycine
Guanidineacetic acid
[(aminoiminomethyl)amino]-Acetic acid
(carboxymethyl)-Guanidine
Betasyamine
α-Guanidinoacetic acid
N-Amidinoglycine
Guanidylacetic acid
amidinoglycine
N-(Aminoiminomethyl)glycine
N-amidino-Glycine
2-(diaminomethylideneamino)acetic acid
Glycine, N-(aminoiminomethyl)-
2-[[Amino(imino)methyl]amino]acetic acid
Glycocyamine
N-Carbamimidoylglycine
a-Guanidinoacetic acid
Carbamimidamidoacetic acid
Guanidoacetic acid
EINECS 206-529-5
N-Guanylglycine
{[Ammonio(imino)methyl]amino}acetate
Guanidinooacetic Acid
2-Guanidinoacetic acid
Betacyamine
MFCD00004278

Biological Activity

[Description]:

2-Guanidinoacetic acid, a precursor of creatine, is a replacement of dietary arginine and could support overall energy homeostasis of the bird.

[Related Catalog]:

Natural Products >> Others

Research Areas >> Others

[Target]

Human Endogenous Metabolite

[References]

[1]. Dilger RN, et al. Dietary guanidino acetic acid is an efficacious replacement for arginine for young chicks. Poult Sci. 2013 Jan;92(1):171-7.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
294.2±42.0 °C at 760 mmHg

[ Melting Point ]:
300 °C(lit.)

[ Molecular Formula ]:
C₃H₇N₃O₂

[ Molecular Weight ]:
117.107

[ Flash Point ]:
131.7±27.9 °C

[ Exact Mass ]:
117.053825

[ PSA ]:
99.20000

[ LogP ]:
-1.85

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.596

[ Water Solubility ]:
6 M NaOH : 50 mg/mL, clear, colorless

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
MB7700000

[ HS Code ]:
29252000

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2925290090

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

High-throughput tandem mass spectrometry multiplex analysis for newborn urinary screening of creatine synthesis and transport disorders, Triple H syndrome and OTC deficiency.

Clin. Chim. Acta 436 , 249-55, (2014)

Creatine synthesis and transport disorders, Triple H syndrome and ornithine transcarbamylase deficiency are treatable inborn errors of metabolism. Early screening of patients was found to be beneficia...

Detection of autosomal dominant polycystic kidney disease by NMR spectroscopic fingerprinting of urine.

Kidney Int. 79(11) , 1244-53, (2011)

Autosomal dominant polycystic kidney disease (ADPKD) is a frequent cause of kidney failure; however, urinary biomarkers for the disease are lacking. In a step towards identifying such markers, we used...

Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations.

Kidney Int. 59(6) , 2267-72, (2001)

Hyperhomocysteinemia is a risk factor for atherosclerosis that is common in chronic renal failure (CRF), but its cause is unknown. Homocysteine metabolism is linked to betaine-homocysteine methyl tran...