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7-Methoxyisoflavone

Names

[ CAS No. ]:
1621-56-3

[ Name ]:
7-Methoxyisoflavone

[Synonym ]:
7-methoxy-3-phenylchromone
7-Methoxy-3-phenyl-chromen-4-on
7-methoxy-3-phenyl-4H-1-benzopyran-4-one
7-methoxy-3-phenyl-4H-chromen-4-one
7-Methoxy Isoflavone
7-methoxy-3-phenyl-chromen-4-one
7-Methoxyisoflavone

Biological Activity

[Description]:

7-Methoxyisoflavone is an isoflavone derivative and also an activator of adenosine monophosphate-activated protein kinase (AMPK).

[Related Catalog]:

Signaling Pathways >> Epigenetics >> AMPK
Signaling Pathways >> PI3K/Akt/mTOR >> AMPK
Research Areas >> Cancer
Natural Products >> Flavonoids
Research Areas >> Metabolic Disease

[Target]

AMPK[1]


[In Vitro]

7-Methoxyisoflavone is an isoflavone derivative and also an activator of adenosine monophosphate-activated protein kinase (AMPK). When serum-starved cells are treated with 10 % FBS in the presence of 7-methoxyisoflavone, the serum-induced decrease in AMPK phosphorylation is prevented[1].

[References]

[1]. Hyeryoung Jung, et al. Isoflavones as modulators of adenosine monophosphate-activated protein kinase. Applied Biological Chemistry. 2016. 59, 217-225.


[Related Small Molecules]

Dorsomorphin dihydrochloride | Acadesine (AICAR) | A-769662 | Phenformin (hydrochloride) | Bempedoic Acid | Flufenamic Acid | WZ 4003 | PF 06409577 | Dantron | O-304 | 6-Gingerol | HTH 01-015 | YLF-466D | Ampkinone

Chemical & Physical Properties

[ Density]:
1.24g/cm3

[ Boiling Point ]:
421.2ºC at 760 mmHg

[ Molecular Formula ]:
C16H12O3

[ Molecular Weight ]:
252.26500

[ Flash Point ]:
200.3ºC

[ Exact Mass ]:
252.07900

[ PSA ]:
39.44000

[ LogP ]:
3.46860

[ Vapour Pressure ]:
2.66E-07mmHg at 25°C

[ Index of Refraction ]:
1.614

[ Storage condition ]:
2-8℃

Safety Information

[ HS Code ]:
2932999099

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2914509090

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%


Related Compounds

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