2-Bromoacetophenone
Names
[ CAS No. ]:
70-11-1
[ Name ]:
2-Bromoacetophenone
[Synonym ]:
2-Bromo-1-Phenylethan-1-One
α-Bromoacetophenone
MFCD00000195
Phenacyl Bromide
EINECS 200-724-9
Ethanone, 2-bromo-1-phenyl-
2-Bromo-1-phenylethanone
2-Bromoacetophenone
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
253.4±0.0 °C at 760 mmHg
[ Melting Point ]:
48-51 °C(lit.)
[ Molecular Formula ]:
C8H7BrO
[ Molecular Weight ]:
199.045
[ Flash Point ]:
78.4±7.2 °C
[ Exact Mass ]:
197.968018
[ PSA ]:
17.07000
[ LogP ]:
2.19
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.570
[ Storage condition ]:
2-8°C
[ Stability ]:
Stable. Incompatible with strong bases, strong oxidizing agents. Combustible.
[ Water Solubility ]:
PRACTICALLY INSOLUBLE
MSDS
Safety Information
[ Symbol ]:
GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
C:Corrosive
[ Risk Phrases ]:
R20/21/22;R34
[ Safety Phrases ]:
S26-S36/37/39-S45
[ RIDADR ]:
UN 2645 6.1/PG 2
[ WGK Germany ]:
3
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
[ HS Code ]:
2914700090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2914700090
[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%
Articles
Bioorg. Med. Chem. 23(9) , 2024-34, (2015)
Recently we described a novel pyranopyridine inhibitor (MBX2319) of RND-type efflux pumps of the Enterobacteriaceae. MBX2319 (3,3-dimethyl-5-cyano-8-morpholino-6-(phenethylthio)-3,4-dihydro-1H-pyrano[...
Nucleophilic heterocyclic carbene as a novel catalyst for cyclopropanation of cyano acrylates.Org. Biomol. Chem. 8(4) , 901-5, (2010)
Nucleophilic heterocyclic carbenes (NHCs) have been used for the first time as catalysts in the cyclopropanation of ethyl cyanocinnamates with phenacyl bromide by Michael-initiated ring-closure (MIRC)...
Bromoacetophenone-based photonucleases: photoinduced cleavage of DNA by 4'-bromoacetophenone-pyrrolecarboxamide conjugates.Org. Lett. 1(13) , 2117-20, (1999)
[formula: see text] 4'-Bromoacetophenone derivatives which upon excitation can generate monophenyl radicals capable of hydrogen atom abstraction were investigated as photoinducible DNA cleaving agents...