PknB-IN-2

Modify Date: 2024-01-14 14:10:03

PknB-IN-2 structure	Common Name	PknB-IN-2
	CAS Number	500015-22-5	Molecular Weight	460.56
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₃₂N₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PknB-IN-2

PknB-IN-2 (Compound 10) is a Mycobacterium tuberculosis protein kinase B (PknB) inhibitor with an IC50 of 12.1 μM[1].

Name	PknB-IN-2

Description	PknB-IN-2 (Compound 10) is a Mycobacterium tuberculosis protein kinase B (PknB) inhibitor with an IC50 of 12.1 μM[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	IC50: 12.1 μM (PknB)[1]
In Vitro	PknB-IN-2 (Compound 10) shows encouraging growth inhibition activity toward the M. tuberculosis H37Rv strain, with a MIC value of 6.2 μg/mL[1].
References	[1]. Thongdee P, et al. Virtual Screening Identifies Novel and Potent Inhibitors of Mycobacterium tuberculosis PknB with Antibacterial Activity. J Chem Inf Model. 2022 Aug 22.

Molecular Formula	C₂₈H₃₂N₂O₄
Molecular Weight	460.56

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