COX/5-LOX-IN-1

Modify Date: 2024-01-09 15:58:20

COX/5-LOX-IN-1 Structure
COX/5-LOX-IN-1 structure
Common Name COX/5-LOX-IN-1
CAS Number 2468802-82-4 Molecular Weight 294.43
Density N/A Boiling Point N/A
Molecular Formula C18H30O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of COX/5-LOX-IN-1


COX/5-LOX-IN-1 (compound 6b) is a potent and dual inhibitor of COX/5-LOX with IC50s of 1.07, 0.55, and 0.28 μM for COX-1, COX-2, and 5-LOX enzyme, respectively. COX/5-LOX-IN-1 has the potential for the research of inflammation diseases[1].

 Names

Name COX/5-LOX-IN-1

 COX/5-LOX-IN-1 Biological Activity

Description COX/5-LOX-IN-1 (compound 6b) is a potent and dual inhibitor of COX/5-LOX with IC50s of 1.07, 0.55, and 0.28 μM for COX-1, COX-2, and 5-LOX enzyme, respectively. COX/5-LOX-IN-1 has the potential for the research of inflammation diseases[1].
Related Catalog
References

[1]. Sisa M, et al. Synthesis, inhibitory activity and in silico docking of dual COX/5-LOX inhibitors with quinone and resorcinol core. Eur J Med Chem. 2020;204:112620.

 Chemical & Physical Properties

Molecular Formula C18H30O3
Molecular Weight 294.43
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