COX-2/15-LOX-IN-1

Modify Date: 2025-08-25 17:39:51

COX-2/15-LOX-IN-1 structure	Common Name	COX-2/15-LOX-IN-1
	CAS Number	2413565-15-6	Molecular Weight	467.63
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₁N₇S₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of COX-2/15-LOX-IN-1

COX-2/15-LOX-IN-1 (Compound 14) is a COX-2 and 15-lipoxygenase enzyme (15-LOX) inhibitor with IC50 values of 10.65, 0.075 and 2.98 μM against COX-1, COX-2 and 15-LOX, respectively. COX-2/15-LOX-IN-1 shows anti-inflammatory activity[1].

Name	COX-2/15-LOX-IN-1

Description	COX-2/15-LOX-IN-1 (Compound 14) is a COX-2 and 15-lipoxygenase enzyme (15-LOX) inhibitor with IC50 values of 10.65, 0.075 and 2.98 μM against COX-1, COX-2 and 15-LOX, respectively. COX-2/15-LOX-IN-1 shows anti-inflammatory activity[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX Signaling Pathways >> Metabolic Enzyme/Protease >> 5-Lipoxygenase
Target	COX-1:10.65 μM (IC50) COX-2:0.075 μM (IC50) 15-LOX:2.98 μM (IC50)
References	[1]. Maghraby MT, et al. Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes. Bioorg Med Chem. 2020 Apr 1;28(7):115403.

Molecular Formula	C₂₁H₂₁N₇S₃
Molecular Weight	467.63

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COX-2/15-LOX-IN-1

Use of COX-2/15-LOX-IN-1

Names

COX-2/15-LOX-IN-1 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.