COX-2/5-LOX-IN-1
Modify Date: 2025-08-27 18:42:42
COX-2/5-LOX-IN-1 structure
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Common Name | COX-2/5-LOX-IN-1 | ||
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| CAS Number | 2410384-50-6 | Molecular Weight | 383.83 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H10ClN3O4S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of COX-2/5-LOX-IN-1COX-2/5-LOX-IN-1 (compound 3a) is a potent and dual inhibitor of COX-2/5-LOX. COX-2/5-LOX-IN-1 is a benzothiophen-2-yl pyrazole carboxylic acid derivative. COX-2/5-LOX-IN-1 shows the most potent analgesic and anti-inflammatory activities surpassing that of Celecoxib and Indomethacin. COX-2/5-LOX-IN-1 shows potent COX-1, COX-2 and 5-LOX inhibitory activity with IC50s of 12.13, 0.4 and 4.96 μM, respectively[1]. |
| Name | COX-2/5-LOX-IN-1 |
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| Description | COX-2/5-LOX-IN-1 (compound 3a) is a potent and dual inhibitor of COX-2/5-LOX. COX-2/5-LOX-IN-1 is a benzothiophen-2-yl pyrazole carboxylic acid derivative. COX-2/5-LOX-IN-1 shows the most potent analgesic and anti-inflammatory activities surpassing that of Celecoxib and Indomethacin. COX-2/5-LOX-IN-1 shows potent COX-1, COX-2 and 5-LOX inhibitory activity with IC50s of 12.13, 0.4 and 4.96 μM, respectively[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C14H10ClN3O4S2 |
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| Molecular Weight | 383.83 |
| InChIKey | MBYVVQGJJDBRKH-UHFFFAOYSA-N |
| SMILES | NS(=O)(=O)c1ccc(-n2nc(C(=O)O)cc2-c2ccc(Cl)s2)cc1 |