COX-2/5-LOX-IN-2
Modify Date: 2025-09-05 17:06:38
COX-2/5-LOX-IN-2 structure
|
Common Name | COX-2/5-LOX-IN-2 | ||
|---|---|---|---|---|
| CAS Number | 2410384-59-5 | Molecular Weight | 399.44 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H13N3O4S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of COX-2/5-LOX-IN-2COX-2/5-LOX-IN-2 (5b) is a potent and dual inhibitor of COX-2/5-LOX. COX-2/5-LOX-IN-2 is a benzothiophen-2-yl pyrazole carboxylic acid derivative. COX-2/5-LOX-IN-2 shows the most potent analgesic and anti-inflammatory activities surpassing that of Celecoxib and Indomethacin. COX-2/5-LOX-IN-2 shows potent COX-1, COX-2 and 5-LOX inhibitory activity with IC50s of 5.40, 0.01 and 1.78 μM, respectively[1]. |
| Name | COX-2/5-LOX-IN-2 |
|---|
| Description | COX-2/5-LOX-IN-2 (5b) is a potent and dual inhibitor of COX-2/5-LOX. COX-2/5-LOX-IN-2 is a benzothiophen-2-yl pyrazole carboxylic acid derivative. COX-2/5-LOX-IN-2 shows the most potent analgesic and anti-inflammatory activities surpassing that of Celecoxib and Indomethacin. COX-2/5-LOX-IN-2 shows potent COX-1, COX-2 and 5-LOX inhibitory activity with IC50s of 5.40, 0.01 and 1.78 μM, respectively[1]. |
|---|---|
| Related Catalog | |
| References |
| Molecular Formula | C18H13N3O4S2 |
|---|---|
| Molecular Weight | 399.44 |
| InChIKey | WQYDAOYIYVNTGB-UHFFFAOYSA-N |
| SMILES | NS(=O)(=O)c1ccc(-n2nc(C(=O)O)cc2-c2cc3ccccc3s2)cc1 |