2358849-47-3

2358849-47-3 structure
2358849-47-3 structure
  • Name: COX-1/2-IN-1
  • Chemical Name: COX-1/2-IN-1
  • CAS Number: 2358849-47-3
  • Molecular Formula: C15H10BrClN2O
  • Molecular Weight: 349.61
  • Catalog: Signaling Pathways Immunology/Inflammation COX
  • Create Date: 2022-05-30 15:04:07
  • Modify Date: 2025-08-26 12:21:28
  • COX-1/2-IN-2 is a potent COX1/2 inhibitor. COX-1/2-IN-2 exhibits significant inhibitory effect against COX-1 and COX-2 inhibitor with IC50 values of 13.9 ± 3.21 µM and 6.4±0.74 µM, respectively[1].

Name COX-1/2-IN-1
Description COX-1/2-IN-2 is a potent COX1/2 inhibitor. COX-1/2-IN-2 exhibits significant inhibitory effect against COX-1 and COX-2 inhibitor with IC50 values of 13.9 ± 3.21 µM and 6.4±0.74 µM, respectively[1].
Related Catalog
Target

COX-1:9.7±0.09 μM (IC50)

COX-2:4.6±1.45 μM (IC50)

References

[1]. Malose J. Mphahlele, et al. Synthesis, in vitro and in silico enzyme (COX-1/2 & LOX-5), free radical scavenging and cytotoxicity profiling of the 2,4-dicarbo substituted quinazoline 3-oxides. Medicinal Chemistry Research volume 31, pages146–164 (2022)

Molecular Formula C15H10BrClN2O
Molecular Weight 349.61
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