COX/5-LOX-IN-1

Names

[ CAS No. ]:
2468802-82-4

[ Name ]:
COX/5-LOX-IN-1

Biological Activity

[Description]:

COX/5-LOX-IN-1 (compound 6b) is a potent and dual inhibitor of COX/5-LOX with IC50s of 1.07, 0.55, and 0.28 μM for COX-1, COX-2, and 5-LOX enzyme, respectively. COX/5-LOX-IN-1 has the potential for the research of inflammation diseases[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology
Signaling Pathways >> Immunology/Inflammation >> COX

[References]

[1]. Sisa M, et al. Synthesis, inhibitory activity and in silico docking of dual COX/5-LOX inhibitors with quinone and resorcinol core. Eur J Med Chem. 2020;204:112620.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H30O3

[ Molecular Weight ]:
294.43

Related Compounds