eIF4A3-IN-16

Modify Date: 2024-01-22 10:50:06

eIF4A3-IN-16 structure	Common Name	eIF4A3-IN-16
	CAS Number	1402931-74-1	Molecular Weight	504.53
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₂₈O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of eIF4A3-IN-16

eIF4A3-IN-16 (compound 60) is a silvestrol (HY-13251) analogue. eIF4A3-IN-16 interferes the assembling of eIF4F translation complex with EC50s of 1, 30 and 1 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-16 can be used for the research of human cancer pathogenesis[1].

Name	eIF4A3-IN-16

Description	eIF4A3-IN-16 (compound 60) is a silvestrol (HY-13251) analogue. eIF4A3-IN-16 interferes the assembling of eIF4F translation complex with EC50s of 1, 30 and 1 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-16 can be used for the research of human cancer pathogenesis[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Eukaryotic Initiation Factor (eIF)
References	[1]. Liu T, et al. Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors. J Med Chem. 2012 Oct 25;55(20):8859-78.

Molecular Formula	C₂₉H₂₈O₈
Molecular Weight	504.53

eIF4A3-IN-16

Use of eIF4A3-IN-16

Names

eIF4A3-IN-16 Biological Activity

Chemical & Physical Properties