e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Chemistry–A European Journal

Development of a General Non??Noble Metal Catalyst for the Benign Amination of Alcohols with Amines and Ammonia

X Cui, X Dai, Y Deng, F Shi

Index: Cui, Xinjiang; Dai, Xingchao; Deng, Youquan; Shi, Feng Chemistry - A European Journal, 2013 , vol. 19, # 11 p. 3665 - 3675

Full Text: HTML

Citation Number: 39

Abstract

Abstract The N-alkylation of amines or ammonia with alcohols is a valuable route for the synthesis of N-alkyl amines. However, as a potentially clean and economic choice for N- alkyl amine synthesis, non-noble metal catalysts with high activity and good selectivity are rarely reported. Normally, they are severely limited due to low activity and poor generality. Herein, a simple NiCuFeO x catalyst was designed and prepared for the N-alkylation of ...

Methylbenzylalcohol Structure

Methylbenzylalcohol

Benzylamine Structure

~83%

N-Benzyl-1-phenylethanamine Structure

N-Benzyl-1-phen...

Benzyl alcohol Structure

~%

N-Benzyl-1-phenylethanamine Structure

N-Benzyl-1-phen...

2-Ethyl-1-butanol Structure

2-Ethyl-1-butanol

~88%

2-Ethyl-N-(2-ethylbutyl)-1-butanamine Structure

2-Ethyl-N-(2-et...

morpholine Structure

4-Methoxybenzyl alcohol Structure

4-Methoxybenzyl...

~92%

4-[(4-methoxyphenyl)methyl]morpholine Structure

4-[(4-methoxyph...

Dioctylamine Structure

Benzyl alcohol Structure

~86%

N-benzyl-N-octyloctan-1-amine Structure

N-benzyl-N-octy...

p-Toluidine Structure

4-Chloroaniline Structure

4-Chloroaniline

Structure

Benzyl alcohol Structure

~%

Detail

Structure

Cyclohexanol Structure

~10%

N-Cyclohexylaniline Structure

N-Cyclohexylaniline

Thiophen-2-ylmethanol Structure

Thiophen-2-ylme...

Dimethylamine Structure

~75%

2-Thenylamine, N,N-dimethyl- Structure

2-Thenylamine, ...

N-Methylbenzylamine Structure

N-Methylbenzylamine

Cyclohexanol Structure

~80%

N-benzyl-N-methylcyclohexanamine Structure

N-benzyl-N-meth...

Pyrrolidine Structure

Benzyl alcohol Structure

~92%

1-benzylpyrrolidine Structure

1-benzylpyrrolidine

Benzyl alcohol Structure

~%

1-benzylpyrrolidine Structure

1-benzylpyrrolidine

1-Hexanol Structure

~58%

Dihexylamine Structure

n-butylamine Structure

Benzyl alcohol Structure

~66%

Benzylbutylamine Structure

Benzylbutylamine

p-tolylmethanol Structure

p-tolylmethanol

p-Toluidine Structure

~88%

4-methyl-N-[(4-methylphenyl)methyl]aniline Structure

4-methyl-N-[(4-...

Dodecanamine Structure

Benzyl alcohol Structure

~84%

4-methyl-N-[(4-methylphenyl)methyl]aniline Structure

4-methyl-N-[(4-...

1,4-Butanediol Structure

2,6-xylidine Structure

~90%

PYRROLIDINE, 1-(2,6-DIMETHYLPHENYL)- Structure

PYRROLIDINE, 1-...

p-Anisidine Structure

Cyclohexanol Structure

~92%

N-cyclohexyl-4-methoxyaniline Structure

N-cyclohexyl-4-...

Methylbenzylalcohol Structure

Methylbenzylalcohol

p-Toluidine Structure

~91%

4-methyl-N-(1-phenylethyl)aniline Structure

4-methyl-N-(1-p...

Cyclohexylmethanol Structure

Cyclohexylmethanol

~84%

1-cyclohexyl-N-(cyclohexylmethyl)methanamine Structure

1-cyclohexyl-N-...

2-pyridone Structure

~65%

2-Aminopyridine Structure

2-Aminopyridine

1-Aminonaphthalene Structure

1-Aminonaphthalene

Cyclohexanol Structure

~86%

N-cyclohexylnaphthalen-1-amine Structure

N-cyclohexylnap...

4-Methoxybenzylamine Structure

4-Methoxybenzylamine

~93%

dianisylamine Structure

4-Methoxybenzyl alcohol Structure

4-Methoxybenzyl...

~70%

dianisylamine Structure

1,4-Butanediol Structure

p-Toluidine Structure

~84%

PYRROLIDINE, 1-(4-METHYLPHENYL)- Structure

PYRROLIDINE, 1-...

p-Toluidine Structure

Cyclohexanol Structure

~86%

N-cyclohexyl-4-methylaniline Structure

N-cyclohexyl-4-...

1,4-Butanediol Structure

1-Aminonaphthalene Structure

1-Aminonaphthalene

~73%

1-(1-NAPHTHYL)PYRROLIDINE Structure

1-(1-NAPHTHYL)P...

p-Toluidine Structure

Isopropanol Structure

~82%

n-isopropyl-p-toluidine Structure

n-isopropyl-p-t...

p-Toluidine Structure

Butanol Structure

~78%

N-N-BUTYL-P-TOLUIDINE Structure

N-N-BUTYL-P-TOL...

Phenethyl alcohol Structure

Phenethyl alcohol

~85%

N-phenethyl-2-phenyl-ethanamine Structure

N-phenethyl-2-p...

p-tolylmethanol Structure

p-tolylmethanol

Structure

p-chlorobenzylalcohol Structure

p-chlorobenzyla...

Benzyl alcohol Structure

~%

Detail

2-Pentanol Structure

~73%

1,1'-dimethyldibutylamine Structure

1,1'-dimethyldi...

p-tolylmethanol Structure

p-tolylmethanol

Dimethylamine Structure

~82%

BENZENEMETHANAMINE, N,N,4-TRIMETHYL- Structure

BENZENEMETHANAM...

p-tolylmethanol Structure

p-tolylmethanol

Structure

p-chlorobenzylalcohol Structure

p-chlorobenzyla...

Benzyl alcohol Structure

~%

Detail

morpholine Structure

Benzyl alcohol Structure

~87%

4-Benzylmorpholine Structure

4-Benzylmorpholine

p-Toluidine Structure

4-Chloroaniline Structure

4-Chloroaniline

Structure

Benzyl alcohol Structure

~%

Detail

3,3-Diphenyl-1-propanol Structure

3,3-Diphenyl-1-...

Dimethylamine Structure

~84%

N,N-Dimethyl-3,3-diphenyl-1-propanamine Structure

N,N-Dimethyl-3,...

Phenethyl alcohol Structure

Phenethyl alcohol

p-Toluidine Structure

~90%

4-methyl-N-(2-phenylethyl)aniline Structure

4-methyl-N-(2-p...

1-Dodecanol Structure

p-Toluidine Structure

~84%

N-dodecyl-4-methylaniline Structure

N-dodecyl-4-met...

4-Chloroaniline Structure

4-Chloroaniline

Cyclohexanol Structure

~78%

4-chloro-N-cyclohexylaniline Structure

4-chloro-N-cycl...

Dimethylamine Structure

4-Methoxybenzyl alcohol Structure

4-Methoxybenzyl...

~90%

Benzenemethanamine,4-methoxy-N,N-dimethyl- Structure

Benzenemethanam...

Piperonyl alcohol Structure

Piperonyl alcohol

~71%

1-(1,3-benzodioxol-5-yl)-N-(1,3-benzodioxol-5-ylmethyl)methanamine Structure

1-(1,3-benzodio...

1,4-Butanediol Structure

4,4′-methylenedianiline Structure

4,4′-methylened...

~80%

1-[4-[(4-pyrrolidin-1-ylphenyl)methyl]phenyl]pyrrolidine Structure

1-[4-[(4-pyrrol...

Dodecanamine Structure

~91%

di-n-Decylamine Structure

di-n-Decylamine

Decan-1-ol Structure

~78%

di-n-Decylamine Structure

di-n-Decylamine

Piperidine Structure

Benzyl alcohol Structure

~95%

1-Benzylpiperidine Structure

1-Benzylpiperidine

Methanol Structure

2-Pyridylethylamine Structure

2-Pyridylethylamine

~77%

Betahistine Structure

p-tolylmethanol Structure

p-tolylmethanol

Structure

p-chlorobenzylalcohol Structure

p-chlorobenzyla...

Benzyl alcohol Structure

~%

Detail

Piperonyl alcohol Structure

Piperonyl alcohol

Dimethylamine Structure

~89%

1-(BENZO[D][1,3]DIOXOL-5-YL)-N,N-DIMETHYLMETHANAMINE Structure

1-(BENZO[D][1,3...

Reductive Amination of Aldehydes and Amines with an Efficien...

[Yang, Huimin; Cui, Xinjiang; Deng, Youquan; Shi, Feng Synthetic Communications, 2014 , vol. 44, # 9 p. 1314 - 1322]

Reductive amination of aromatic aldehydes and ketones with n...

[Saxena, Ira; Borah, Ruli; Sarma, Jadab C. Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 4 p. 503 - 504]

Reduction of imines with zinc borohydride supported on silic...

[Ranu, Brindaban C.; Sarkar, Arunkanti; Majee, Adinath Journal of Organic Chemistry, 1997 , vol. 62, # 6 p. 1841 - 1842]

Cp∗ Ir-catalyzed N-alkylation of amines with alcohols. A ver...

[Fujita, Ken-ichi; Enoki, Youichiro; Yamaguchi, Ryohei Tetrahedron, 2008 , vol. 64, # 8 p. 1943 - 1954]

Untersuchungen zum Mechanismus der Rhodium (I)-katalysierten...

[Brune, Hans-Albert; Unsin, Josef; Hemmer, Reinhard; Reichhardt, Monika Journal of Organometallic Chemistry, 1989 , vol. 369, p. 335 - 342]