2-pyridone

Modify Date: 2024-01-02 12:21:30

2-pyridone Structure
2-pyridone structure
Common Name 2-pyridone
CAS Number 142-08-5 Molecular Weight 95.099
Density 1.1±0.1 g/cm3 Boiling Point 323.7±15.0 °C at 760 mmHg
Molecular Formula C5H5NO Melting Point 105-107 °C(lit.)
MSDS Chinese USA Flash Point 181.1±5.3 °C
Symbol GHS06
GHS06
Signal Word Danger

 Names

Name pyridin-2-ol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 323.7±15.0 °C at 760 mmHg
Melting Point 105-107 °C(lit.)
Molecular Formula C5H5NO
Molecular Weight 95.099
Flash Point 181.1±5.3 °C
Exact Mass 95.037117
PSA 33.12000
LogP -0.58
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.514
Storage condition Store at RT.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UV1144050
CHEMICAL NAME :
2(1H)-Pyridone
CAS REGISTRY NUMBER :
142-08-5
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C5-H5-N-O
MOLECULAR WEIGHT :
95.11

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
410 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 23,815,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 93,143,1953 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
594 mg/kg/5D-I
TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes
REFERENCE :
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 85,173,1996

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H315-H319-H335
Precautionary Statements Missing Phrase - N15.00950417-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR UN2811
WGK Germany 3
RTECS UV1144050
Packaging Group III
Hazard Class 6.1
HS Code 2933399090

 Synthetic Route

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles39

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 Synonyms

pyridinol
2-PYRIDON
pyridinyl-6'-ol
2(1H)-Pyridone
2-oxypyridine
A-PYRIDONE
2-pyridone
2-hydroxy-pyridine
2-pyridinone
EINECS 205-520-3
2-PYRIDOL
Pyridin-2(1H)-one
2-pyridinol
pyridinone
Pyridone-2
2(1H)-Pyridinone
2-Oxopyridine
AURORA KA-3075
pyridone
2-Hydroxypyridine
pyridin-2-ol
1H-2-Pyridone
MFCD00006268
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