p-chlorobenzylalcohol

Modify Date: 2024-01-01 20:15:14

p-chlorobenzylalcohol Structure
p-chlorobenzylalcohol structure
Common Name p-chlorobenzylalcohol
CAS Number 873-76-7 Molecular Weight 142.583
Density 1.2±0.1 g/cm3 Boiling Point 234.1±15.0 °C at 760 mmHg
Molecular Formula C7H7ClO Melting Point 68-71 °C(lit.)
MSDS Chinese USA Flash Point 95.4±20.4 °C

 Names

Name 4-Chlorobenzyl Alcohol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 234.1±15.0 °C at 760 mmHg
Melting Point 68-71 °C(lit.)
Molecular Formula C7H7ClO
Molecular Weight 142.583
Flash Point 95.4±20.4 °C
Exact Mass 142.018539
PSA 20.23000
LogP 1.63
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.566
Stability Stable. Incompatible with acid chlorides, acid anhydrides, acids, oxidizing agents. Combustible.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DN9242000
CHEMICAL NAME :
Benzyl alcohol, p-chloro-
CAS REGISTRY NUMBER :
873-76-7
LAST UPDATED :
199710
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C7-H7-Cl-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3840 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 55(5),13,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 55(5),13,1990

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes F+
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS DN9242000
HS Code 29062900

 Synthetic Route

 Customs

HS Code 2906299090
Summary 2906299090 other aromatic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Articles1

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S-benzylisothiourea derivatives as small-molecule inhibitors of indoleamine-2,3-dioxygenase.

Bioorg. Med. Chem. Lett. 20 , 5126-9, (2010)

S-benzylisothiourea 3a was discovered by its ability to inhibit indoleamine-2,3-dioxygenase (IDO) in our screening program. Subsequent optimization of the initial hit 3a lead to the identification of ...

 Synonyms

4-Chlorobenzyl alcohol
p-chlorobenzylalcohol
EINECS 212-852-2
Benzenemethanol, 4-chloro-
(4-Chlorophenyl)methanol
MFCD00004652