p-chlorobenzylalcohol

p-chlorobenzylalcohol Structure
p-chlorobenzylalcohol structure
Common Name p-chlorobenzylalcohol
CAS Number 873-76-7 Molecular Weight 142.583
Density 1.2±0.1 g/cm3 Boiling Point 234.1±15.0 °C at 760 mmHg
Molecular Formula C7H7ClO Melting Point 68-71 °C(lit.)
MSDS Chinese USA Flash Point 95.4±20.4 °C

S-benzylisothiourea derivatives as small-molecule inhibitors of indoleamine-2,3-dioxygenase.

Bioorg. Med. Chem. Lett. 20 , 5126-9, (2010)

S-benzylisothiourea 3a was discovered by its ability to inhibit indoleamine-2,3-dioxygenase (IDO) in our screening program. Subsequent optimization of the initial hit 3a lead to the identification of sub-muM inhibitors 3r and 10h, both of which suppressed kyn...