The Journal of Organic Chemistry

Reduction of imines with zinc borohydride supported on silica gel. Highly stereoselective synthesis of substituted cyclohexylamines

BC Ranu, A Sarkar, A Majee

Index: Ranu, Brindaban C.; Sarkar, Arunkanti; Majee, Adinath Journal of Organic Chemistry, 1997 , vol. 62, # 6 p. 1841 - 1842

Full Text: HTML

Citation Number: 26

Abstract

The reduction of imines to the corresponding amines is a very useful transformation in organic synthesis since amines constitute important precursors to compounds that are of much interest in pharmaceutical and agricultural industries. 1 The stereochemistry of such carbonnitrogen π bond reduction is also of great importance in synthetic applications; unfortunately, only a few reports are available in the literature dealing with this aspect. 2 In ...