Fusarenon-X
Fusarenon-X structure
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Common Name | Fusarenon-X | ||
|---|---|---|---|---|
| CAS Number | 23255-69-8 | Molecular Weight | 354.352 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 569.2±50.0 °C at 760 mmHg | |
| Molecular Formula | C17H22O8 | Melting Point | 91-92℃ | |
| MSDS | Chinese USA | Flash Point | 208.4±23.6 °C | |
| Symbol |
GHS02, GHS07 |
Signal Word | Danger | |
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Apoptosis and gene expression in the developing mouse brain of fusarenon-X-treated pregnant mice.
Toxicol. Lett. 229(1) , 292-302, (2014) Fusarenon-X (FX), a type B trichothecene mycotoxin, is mainly produced by Fusarium crookwellense, which occurs naturally in agricultural commodities, such as wheat and barley. FX has been shown to exert a variety of toxic effects on multiple targets in vitro.... |
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A rapid method with ultra-high-performance liquid chromatography-tandem mass spectrometry for simultaneous determination of five type B trichothecenes in traditional Chinese medicines.
J. Sep. Sci. 33(13) , 1923-32, (2010) A speedy and selective ultra-HPLC-MS/MS method for simultaneous determination of deoxynivalenol (DON), 3-acetyldeoxynivalenol (3-ADON), 15-ADON, nivalenol and fusarenon X in traditional Chinese medicines (TCMs) was developed. The method was based on one-step ... |
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3D QSAR study of the toxicity of trichothecene mycotoxins.
Eur. J. Med. Chem. 44 , 4485-9, (2009) Trichothecene mycotoxins, toxic natural products of fungi from the family Hypocreaceae, are potent inhibitors of protein synthesis. The application of 3D QSAR to these toxins explored the structural basis for their biological activities. A CoMFA (Q(2)=0.619, ... |
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Occurrence and distribution of 13 trichothecene toxins in naturally contaminated maize plants in Germany.
Toxins (Basel.) 4(10) , 778-87, (2012) The objective of the present study was to monitor the occurrence and distribution of a spectrum of trichothecene toxins in different parts of maize plants. Therefore maize plants were sampled randomly from 13 fields in southwest Germany and the fractions kern... |
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New insights into mycotoxin mixtures: the toxicity of low doses of Type B trichothecenes on intestinal epithelial cells is synergistic.
Toxicol. Appl. Pharmacol. 272(1) , 191-8, (2013) Deoxynivalenol (DON) is the most prevalent trichothecene mycotoxin in crops in Europe and North America. DON is often present with other type B trichothecenes such as 3-acetyldeoxynivalenol (3-ADON), 15-acetyldeoxynivalenol (15-ADON), nivalenol (NIV) and fusa... |
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Genotyping and phenotyping of Fusarium graminearum isolates from Germany related to their mycotoxin biosynthesis.
Int. J. Food Microbiol. 151(1) , 78-86, (2011) Fusarium graminearum is the most important pathogen causing Fusarium head blight (FHB) of small cereal grains worldwide responsible for quantitative and qualitative yield losses. The presence in crops is often associated with mycotoxin contamination of foodst... |
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Comparison of murine anorectic responses to the 8-ketotrichothecenes 3-acetyldeoxynivalenol, 15-acetyldeoxynivalenol, fusarenon X and nivalenol
Food Chem. Toxicol. 50(6) , 2056-61, (2012) Highlights ► We compare the anorectic effects of 3-ADON, 15- ADON, NIV, FX to those of DON. ► Like DON, 3-ADON and 15-ADON induce transient anorexia. ► FX and NIV induce much longer, persistent anorectic effects than DON or the ADONs. ► IP exposures to tricho... |
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Comparison of emetic potencies of the 8-ketotrichothecenes deoxynivalenol, 15-acetyldeoxynivalenol, 3-acetyldeoxynivalenol, fusarenon X, and nivalenol.
Toxicol. Sci. 131(1) , 279-91, (2013) Although the acute toxic effects of trichothecene mycotoxin deoxynivalenol (DON or vomitoxin), a known cause of human food poisoning, have been well characterized in several animal species, much less is known about closely related 8-ketotrichothecenes that si... |
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A rapid multiresidual determination of type A and type B trichothecenes in wheat flour by HPLC-ESI-MS.
Food Addit. Contam. 22(3) , 251-8, (2005) A new, rapid and sensitive method is reported for the multiresidual determination of type A (diacetoxyscirpenol, HT-2 toxin, T-2 toxin) and type B (nivalenol, deoxynivalenol, fusarenon X, 15-O-acetyl-4-deoxynivalenol) trichothecenes in wheat flour samples. Sa... |
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The activities of mycotoxins derived from Fusarium and related substances in a short-term transformation assay using v-Ha-ras-transfected BALB/3T3 cells (Bhas 42 cells).
Mutat. Res. 630(1-2) , 103-11, (2007) Cell transformation assays using BALB/3T3 cells can mimic the two-stage process of chemical carcinogenesis in experimental animals. A short-term transformation assay using v-Ha-ras-transfected BALB/3T3 cells (Bhas 42 cells), which was developed by Ohmori et a... |