beta-Estradiol 17-hemisuccinate
beta-Estradiol 17-hemisuccinate structure
|
Common Name | beta-Estradiol 17-hemisuccinate | ||
|---|---|---|---|---|
| CAS Number | 7698-93-3 | Molecular Weight | 372.455 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 570.1±50.0 °C at 760 mmHg | |
| Molecular Formula | C22H28O5 | Melting Point | 162-164°C (lit.) | |
| MSDS | Chinese USA | Flash Point | 198.7±23.6 °C | |
| Symbol |
GHS07, GHS08 |
Signal Word | Warning | |
|
Effects of estrogen receptor agonists on regulation of the inflammatory response in astrocytes from young adult and middle-aged female rats.
J. Neuroimmunol. , (2008) Estrogen has been shown to attenuate the inflammatory response following injury or lipopolysaccharide treatment in several organ systems. Estrogen's actions are transduced through two estrogen receptor sub-types, estrogen receptor (ER) -alpha and estrogen rec... |
|
|
Steroid-bovine serum albumin conjugates: molecular characterization and their interaction with androgen and estrogen receptors.
J. Steroid Biochem. 24(5) , 1017-31, (1986) Conjugates of testosterone-3-carboxymethyloxime (T-3-CMO), testosterone-17-hemisuccinate (T-17-HS), 17 beta-estradiol-6-carboxymethyloxime (E-6-CMO), or 17 beta-estradiol-17-hemisuccinate (E-17-HS) and bovine serum albumin (BSA) with varying steroid:protein r... |
|
|
Prevention of bridge binding in immunoassays: a general estradiol tracer structure.
J. Steroid Biochem. 32(2) , 251-7, (1989) Iodinated estradiol tracers were synthesized with three different bridges connecting the radiolabelled moiety to the steroid core: Hemisuccinate, carboxymethyloxime and amide. Taking these iodinated tracers in combination with ten antibodies raised against es... |
|
|
Factors influencing the measurement of oestrone sulphate by dipstick particle capture immunoassay.
J. Immunol. Methods 270(1) , 77-84, (2002) Factors influencing the performance of a dipstick competitive particle capture immunoassay (PCI) for the steroid oestrone sulphate (OS) were investigated. Appropriate 'blocking' of the nitrocellulose dipstick membrane was necessary for the upward flow of micr... |
|
|
Zonal analysis of cytoplasmic steroid hormone receptor levels: replication and synthetic activity in embryonic calf growth cartilage.
Calcif. Tissue Int. 35(6) , 740-4, (1983) Using the dextran charcoal method, a specific steroid receptor for dexamethasone, but not 17 beta-estradiol or 17 alpha-methyltrienolone, was demonstrated in cytosol prepared from mid-gestation fetal calf growth cartilage. Zonal analysis of cytoplasmic recept... |
|
|
Estrogen regulation of dopamine release in the nucleus accumbens: genomic- and nongenomic-mediated effects.
J. Neurochem. 62(5) , 1750-6, (1994) The ability of estrogen to modulate mesolimbic dopamine (DA) was examined using in vivo voltammetry. Estrogen priming (5 micrograms, 48 h) of ovariectomized (ovx) female rats resulted in a slight decrease in K(+)-stimulated DA release measured in the nucleus ... |
|
|
Does postmenopausal bone loss respond to estrogen replacement therapy independent of bone loss rate?
Calcif. Tissue Int. 35(6) , 720-2, (1983) Bone loss in postmenopausal women can be treated by hormonal substitution therapy. We investigated whether rapid bone losers (as opposed to nonrapid losers) respond sufficiently to estrogen treatment. A sample of 88 early postmenopausal women was followed up ... |
|
|
Vascular action of high dose estrogen in rats.
Endocrinol. Jpn. 27(3) , 307-13, (1980) Effects of estradiol hemisuccinate and diethylstilbestrol diphosphate on the cardiovascular system in male rats were examined in vivo and in vitro. In conscious rats, intravenously administered estradiol or diethylstilbestrol inhibited vascular responses to n... |
|
|
Crystal structure of Mycobacterium tuberculosis Rv0760c at 1.50 A resolution, a structural homolog of Delta(5)-3-ketosteroid isomerase.
Biochim. Biophys. Acta 1784(11) , 1625-32, (2008) We have determined the X-ray crystal structure of the Mycobacterium tuberculosis (Mtb) gene product encoded by the open reading frame Rv0760c at 1.50 A resolution by single-wavelength anomalous dispersion (SAD) phasing of diffraction data from crystals of the... |
|
|
Sex steroid effects on extrahypothalamic CNS. I. Estrogen augments neuronal responsiveness to iontophoretically applied glutamate in the cerebellum.
Brain Res. 422(1) , 40-51, (1987) The purpose of this study was to test whether 17 beta-estradiol (E2) could alter neuronal activity or responsiveness to iontophoretically applied amino acid neurotransmitters in an area not reported to contain classical E2 receptors. Such a region is the cere... |