Sodium taurodeoxycholate hydrate
Sodium taurodeoxycholate hydrate structure
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Common Name | Sodium taurodeoxycholate hydrate | ||
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| CAS Number | 207737-97-1 | Molecular Weight | 521.69 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H44NNaO6S | Melting Point | 168ºC (dec.)(lit.) | |
| MSDS | USA | Flash Point | N/A | |
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Shiga toxin glycosphingolipid receptors of Vero-B4 kidney epithelial cells and their membrane microdomain lipid environment.
J. Lipid Res. 56 , 2322-36, (2015) Shiga toxins (Stxs) are produced by enterohemorrhagic Escherichia coli (EHEC), which cause human infections with an often fatal outcome. Vero cell lines, derived from African green monkey kidney, represent the gold standard for determining the cytotoxic effec... |
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Bile acids repress hypoxia-inducible factor 1 signaling and modulate the airway immune response.
Infect. Immun. 82(9) , 3531-41, (2014) Gastroesophageal reflux (GER) frequently occurs in patients with respiratory disease and is particularly prevalent in patients with cystic fibrosis. GER is a condition in which the duodenogastric contents of the stomach leak into the esophagus, in many cases ... |
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Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut.
Proc. Natl. Acad. Sci. U. S. A. 111(20) , 7421-6, (2014) Alterations in the gastrointestinal microbiota have been implicated in obesity in mice and humans, but the key microbial functions influencing host energy metabolism and adiposity remain to be determined. Despite an increased understanding of the genetic cont... |
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Effect of submicellar concentrations of conjugated and unconjugated bile salts on the lipid bilayer membrane.
Langmuir 27 , 13461, (2011) The interaction of submicellar concentrations of various physiologically important unconjugated [sodium deoxycholate (NaDC), sodium cholate (NaC)] and conjugated [sodium glycodeoxycholate (NaGDC), sodium glycocholate (NaGC), sodium taurodeoxycholate (NaTDC), ... |
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Short-term feedback regulation of bile salt uptake by bile salts in rodent liver.
Hepatology 56 , 2387, (2012) The sodium taurocholate cotransporting polypeptide (Ntcp) is the major bile salt uptake transporter at the sinusoidal membrane of hepatocytes. Short-term feedback regulation of Ntcp by primary bile salts has not yet been investigated in vivo. Subcellular loca... |
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Structure–function analysis of the tertiary bile acid TUDCA for the resolution of endoplasmic reticulum stress in intestinal epithelial cells
Biochem. Biophys. Res. Commun. 409 , 610, (2011) Highlights ► TUDCA inhibits the expression of ER stress markers in intestinal epithelial cells. ► TUDCA prohibits the activation of the unfolded protein response in these cells. ► UDCA but not taurine mediates the inhibitory effects of TUDCA. ► The hydrophobi... |
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Polymorphic behavior in protein-surfactant mixtures: the water-bovine serum albumin-sodium taurodeoxycholate system.
J. Phys. Chem. B 110 , 12129, (2006) Mixtures containing water, bovine serum albumin (BSA), and sodium taurodeoxycholate (NaTDC), a component of the bile in mammals, have been investigated in a wide range of composition and pH. Depending on the concentration of both solutes and the pH, solutions... |