IU1

IU1 Structure
IU1 structure
Common Name IU1
CAS Number 314245-33-5 Molecular Weight 300.371
Density 1.2±0.1 g/cm3 Boiling Point 437.0±45.0 °C at 760 mmHg
Molecular Formula C18H21FN2O Melting Point N/A
MSDS Chinese USA Flash Point 218.1±28.7 °C
Symbol GHS05
GHS05
Signal Word Danger

Post-endocytotic Deubiquitination and Degradation of the Metabotropic γ-Aminobutyric Acid Receptor by the Ubiquitin-specific Protease 14.

J. Biol. Chem. 291 , 7156-70, (2016)

Mechanisms controlling the metabotropic γ-aminobutyric acid receptor (GABAB) cell surface stability are still poorly understood. In contrast with many other G protein-coupled receptors (GPCR), it is not subject to agonist-promoted internalization, but is cons...

Ubiquitin-specific protease 14 modulates degradation of cellular prion protein.

Sci. Rep. 5 , 11028, (2015)

Prion diseases are fatal neurodegenerative disorders characterized by the accumulation of prion protein (PrP(C)). To date, there is no effective treatment for the disease. The accumulated PrP, termed PrP(Sc), forms amyloid fibrils and could be infectious. It ...