2',4',6'-Trihydroxyacetophenone Monohydrate

2',4',6'-Trihydroxyacetophenone Monohydrate Structure
2',4',6'-Trihydroxyacetophenone Monohydrate structure
Common Name 2',4',6'-Trihydroxyacetophenone Monohydrate
CAS Number 480-66-0 Molecular Weight 168.147
Density 1.4±0.1 g/cm3 Boiling Point 333.2±22.0 °C at 760 mmHg
Molecular Formula C8H8O4 Melting Point 219-221 °C(lit.)
MSDS Chinese USA Flash Point 169.5±18.8 °C
Symbol GHS07
GHS07
Signal Word Warning

Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: an update for 2009-2010.

Mass Spectrom. Rev. 34(3) , 268-422, (2015)

This review is the sixth update of the original article published in 1999 on the application of MALDI mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings coverage of the literature to the end of 2010. General aspects such as theo...

Optimization of matrix assisted desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) for the characterization of Bacillus and Brevibacillus species.

Anal. Chim. Acta 840 , 49-57, (2014)

Over the past few decades there has been an increased interest in using various analytical techniques for detecting and identifying microorganisms. More recently there has been an explosion in the application of matrix assisted laser desorption ionization tim...

A High-Throughput Mass Spectrometry Assay Coupled with Redox Activity Testing Reduces Artifacts and False Positives in Lysine Demethylase Screening.

J. Biomol. Screen. 20 , 810-20, (2015)

Demethylation of histones by lysine demethylases (KDMs) plays a critical role in controlling gene transcription. Aberrant demethylation may play a causal role in diseases such as cancer. Despite the biological significance of these enzymes, there are limited ...

Visualized absorption of anti-atherosclerotic dipeptide, Trp-His, in Sprague-Dawley rats by LC-MS and MALDI-MS imaging analyses.

Mol. Nutr. Food. Res. 59 , 1541-9, (2015)

The basic dipeptide, Trp-His, was found to show an in vivo anti-atherosclerotic effect when orally administered to apo E-deficient mice. In addition, this dipeptide causes vasorelaxation in contracted rat aorta via suppression of intracellular Ca(2+) signalin...

Comparative glycoprofiling of HIV gp120 immunogens by capillary electrophoresis and MALDI mass spectrometry.

Electrophoresis 36 , 1305-13, (2015)

The human immunodeficiency virus (HIV) envelope glycoprotein (Env) is the primary antigenic feature on the surface of the virus and is of key importance in HIV vaccinology. Vaccine trials with the gp120 subunit of Env are ongoing, with the recent RV144 trial ...

Collision-induced dissociation of aminophospholipids (PE, MMPE, DMPE, PS): an apparently known fragmentation process revisited.

Anal. Bioanal. Chem 407 , 5079-89, (2015)

A new type of low-mass substituted 4-oxazolin product ions of [M + H](+) precursor ions of aminophospholipids (glycerophosphatidylethanolamine, glycerophosphatidyl-N-methylethanolamine, glycerophosphatidyl-N,N-dimethylethanolamine, glycerophosphatidylserine) ...

Ametantrone-based compounds as potential regulators of Tau pre-mRNA alternative splicing.

Org. Biomol. Chem. 13(2) , 452-64, (2014)

Tau pre-mRNA contains a stem-loop structure involved in the regulation of the alternative splicing of tau protein. We describe here a new family of Tau RNA ligands selected by dynamic combinatorial chemistry based on the combination of ametantrone with small ...

Synthesis and tau RNA binding evaluation of ametantrone-containing ligands.

J. Org. Chem. 80(4) , 2155-64, (2015)

We describe the synthesis and characterization of ametantrone-containing RNA ligands based on the derivatization of this intercalator with two neamine moieties (Amt-Nea,Nea) or with one azaquinolone heterocycle and one neamine (Amt-Nea,Azq) as well as its com...

Oligosaccharidic fractions derived from Triticum vulgare extract accelerate tissutal repairing processes in in vitro and in vivo models of skin lesions.

J. Ethnopharmacol. 159 , 198-208, (2014)

Triticum vulgare has been extensively used in traditional medicine thanks to its properties of accelerating tissue repair. The aqueous extract of Triticum vulgare (TVE) is currently an active component used by Farmaceutici Damor in the manufacture of certain ...

Gold-Coated Superparamagnetic Nanoparticles for Single Methyl Discrimination in DNA Aptamers.

Int. J. Mol. Sci. 16 , 27625-39, (2015)

Au- and iron-based magnetic nanoparticles (NPs) are promising NPs for biomedical applications due to their unique properties. The combination of a gold coating over a magnetic core puts together the benefits from adding the magnetic properties to the robust c...