2,6-Dichlorophenol

2,6-Dichlorophenol Structure
2,6-Dichlorophenol structure
Common Name 2,6-Dichlorophenol
CAS Number 87-65-0 Molecular Weight 163.001
Density 1.5±0.1 g/cm3 Boiling Point 219.0±0.0 °C at 760 mmHg
Molecular Formula C6H4Cl2O Melting Point 65 °C
MSDS Chinese USA Flash Point 94.9±15.8 °C
Symbol GHS05
GHS05
Signal Word Danger

cIEF for rapid pKa determination of small molecules: a proof of concept.

Eur. J. Pharm. Sci. 63 , 14-21, (2014)

A capillary isoelectric focusing (cIEF) method was developed for the determination of the ionization constants (pKa) of small molecules. Two approaches used to decrease the electroosmotic flow (EOF) were compared: (i) a hydroxypropylcellulose (HPC) coated cap...

Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).

J. Med. Chem. 48 , 3269-79, (2005)

Growing interest in the use of both the logarithm of the partition coefficient of the neutral species in the alkane/water system (log P(N)(alk)) and the difference between log P(N)(oct) (the logarithm of the partition coefficient of the neutral species in the...

Physico-chemical properties, antioxidant activity and mineral contents of pineapple genotypes grown in china.

Molecules 19(6) , 8518-32, (2014)

The fruit physico-chemical properties, antioxidant activity and mineral contents of 26 pineapple [Ananas comosus (L.) Merr.] genotypes grown in China were measured. The results showed great quantitative differences in the composition of these pineapple genoty...

Novel and simple headspace in-tube microextraction coupled with capillary electrophoresis

J. Chromatogr. A. 1346 , 117-22, (2014)

• The liquid in a separation capillary is used as an acceptor phase. • Extremely simple but powerful way of liquid phase microextraction. • In-tube microextraction is first applied to headspace extraction. • In-tube microextraction is coupled with capillary e...

Determination of chlorophenols in honey samples using in-situ ionic liquid-dispersive liquid-liquid microextraction as a pretreatment method followed by high-performance liquid chromatography.

Food Chem. 174 , 446-51, (2014)

In-situ ionic liquid-dispersive liquid-liquid microextraction (IL-DLLME) method was developed as a pretreatment method for the detection of six chlorophenols (CPs) in honey samples. The hydrophobic ionic liquid [C4MIM][NTf2], formed in-situ by the hydrophilic...

Synthesis of a metal-organic framework confined in periodic mesoporous silica with enhanced hydrostability as a novel fiber coating for solid-phase microextraction.

J. Sep. Sci. 38(7) , 1187-93, (2015)

A metal-organic framework/periodic mesoporous silica (MOF-5@SBA-15) hybrid material has been prepared by using SBA-15 as a matrix. The prepared MOF-5@SBA-15 hybrid material was then deposited on a stainless-steel wire to obtain the fiber for the solid-phase m...

Polypyrrole-montmorillonite nanocomposite as sorbent for solid-phase microextraction of phenolic compounds in water.

J. Sep. Sci. 37(23) , 3526-32, (2014)

A fiber-coated polypyrrole-montmorillonite nanocomposite was prepared for solid-phase microextraction. The fiber coating can be prepared easily; it is mechanically stable and exhibits relatively high thermal stability. The prepared fiber was evaluated for the...

Identification of 4-benzylamino-2-[(4-morpholin-4-ylphenyl)amino]pyrimidine-5-carboxamide derivatives as potent and orally bioavailable STAT6 inhibitors.

Bioorg. Med. Chem. 16 , 6509-21, (2008)

Signal transducers and activators of transcription 6 (STAT6) is a key regulator of the type 2 helper T (Th2) cell immune response and a potential therapeutic target for allergic diseases such as asthma and atopic diseases. To search for potent and orally bioa...

Distribution and formation of chlorophenols and bromophenols in marine and riverine environments.

Chemosphere 77(4) , 552-8, (2009)

To understand the distribution and formation of chlorophenols (CPs) and bromophenols (BPs), we analyzed water and sediment samples collected from the riverine areas and the marine environments near a nuclear power plant (NPP) in Korea. In the seawater, only B...

Michael hydratase alcohol dehydrogenase or just alcohol dehydrogenase?

AMB Express 4 , 30, (2014)

The Michael hydratase - alcohol dehydrogenase (MhyADH) from Alicycliphilus denitrificans was previously identified as a bi-functional enzyme performing a hydration of α,β-unsaturated ketones and subsequent oxidation of the formed alcohols. The investigations ...