Wiskostatin
Wiskostatin structure
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Common Name | Wiskostatin | ||
|---|---|---|---|---|
| CAS Number | 253449-04-6 | Molecular Weight | 426.146 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 320.2±22.0 °C at 760 mmHg | |
| Molecular Formula | C17H18Br2N2O | Melting Point | 153-155ºC | |
| MSDS | Chinese USA | Flash Point | 147.4±22.3 °C | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Claudin-5 is involved in breast cancer cell motility through the N-WASP and ROCK signalling pathways.
J. Exp. Clin. Cancer Res 31 , 43, (2012) Recent studies have shown dysregulation in TJ structure of several cancers including breast. Claudin-5 is a protein member of the TJ structure expressed in both endothelial and epithelial cells. This study examined the level of expression and distribution of ... |
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N-wasp is essential for the negative regulation of B cell receptor signaling.
PLoS Biol. 11 , e1001704, (2013) Negative regulation of receptor signaling is essential for controlling cell activation and differentiation. In B-lymphocytes, the down-regulation of B-cell antigen receptor (BCR) signaling is critical for suppressing the activation of self-reactive B cells; h... |
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Coordinated oscillations in cortical actin and Ca2+ correlate with cycles of vesicle secretion.
Nat. Cell Biol. 14 , 1261-9, (2012) The actin cortex both facilitates and hinders the exocytosis of secretory granules. How cells consolidate these two opposing roles was not well understood. Here we show that antigen activation of mast cells induces oscillations in Ca(2+) and PtdIns(4,5)P(2) l... |