253449-04-6

253449-04-6 structure

Name: Wiskostatin
Chemical Name: 1-(3,6-dibromocarbazol-9-yl)-3-(dimethylamino)propan-2-ol
CAS Number: 253449-04-6
Molecular Formula: C₁₇H₁₈Br₂N₂O
Molecular Weight: 426.146
Catalog: Signaling Pathways Cytoskeleton Arp2/3 Complex
Create Date: 2018-12-31 20:42:48
Modify Date: 2024-01-24 12:50:46
Wiskostatin is a potent and selective inhibitor of neuronal Wiskott-Aldrich syndrome protein (N-WASP)-mediated actin polymerization. Wiskostatin causes a rapid, profound, and irreversible decrease in cellular ATP levels[1].

Name	1-(3,6-dibromocarbazol-9-yl)-3-(dimethylamino)propan-2-ol
Synonyms	1-(3,6-Dibromo-9H-carbazol-9-yl)-3-(dimethylamino)-2-propanol 1-(3,6-dibromo-9H-carbazol-9-yl)-3-(dimethylamino)propan-2-ol 1-(3,6-Dibromo-carbazol-9-yl)-3-dimethylamino-propan-2-ol 1-(3,6-dibromocarbazol-9-yl)-3-dimethylaminopropan-2-ol Wiskostatin 1-(3,6-dibromocarbazol-9-yl)-3-(dimethylamino)propan-2-ol 9H-Carbazole-9-ethanol, 3,6-dibromo-α-[(dimethylamino)methyl]-

Description	Wiskostatin is a potent and selective inhibitor of neuronal Wiskott-Aldrich syndrome protein (N-WASP)-mediated actin polymerization. Wiskostatin causes a rapid, profound, and irreversible decrease in cellular ATP levels[1].
Related Catalog	Signaling Pathways >> Cytoskeleton >> Arp2/3 Complex Research Areas >> Neurological Disease
References	[1]. Guerriero CJ, et al. N-WASP inhibitor wiskostatin nonselectively perturbs membrane transport by decreasing cellular ATP levels. Am J Physiol Cell Physiol. 2007;292(4):C1562-C1566.

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%