2-(9-Oxoacridin-10(9H)-yl)acetic acid
2-(9-Oxoacridin-10(9H)-yl)acetic acid structure
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Common Name | 2-(9-Oxoacridin-10(9H)-yl)acetic acid | ||
|---|---|---|---|---|
| CAS Number | 38609-97-1 | Molecular Weight | 253.253 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 486.6±34.0 °C at 760 mmHg | |
| Molecular Formula | C15H11NO3 | Melting Point | -289ºC (dec.) | |
| MSDS | Chinese USA | Flash Point | 248.1±25.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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[The interferon production by rat spleen and thymus lymphocytes in condititons of hypoacidity].
Fiziol. Zh. 59(1) , 84-8, (2013) The interferon production by rat spleen and thymus lymphocytes in conditions of gastric juice hypoacidity, evoked by 28 days of omeprazole treatment, was studied. It was shown that the spontaneous and induced by PHA and cycloferone interferon titer increases ... |
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[Experimental justification of approaches to pharmacological correction of delayed disorders caused by acute ethylene glycol poisoning].
Eksp. Klin. Farmakol. 75(11) , 31-4, (2012) The development of delayed disorders caused by acute ethylene glycol poisoning has been studied in experiments on male rats. These disorders include chronic renal failure and secondary combined immunodeficiency status of the "circulus vitiosus" type. Urgent p... |
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Species-specific detection of the antiviral small-molecule compound CMA by STING.
EMBO J. 32(10) , 1440-50, (2013) Extensive research on antiviral small molecules starting in the early 1970s has led to the identification of 10-carboxymethyl-9-acridanone (CMA) as a potent type I interferon (IFN) inducer. Up to date, the mode of action of this antiviral molecule has remaine... |
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[An experimental study of the efficiency of cycloferon in the complex chemotherapy of generalized drug-resistant tuberculosis].
Eksp. Klin. Farmakol. 75(9) , 32-6, (2012) The results of an experimental study of the efficiency of cycloferon included in a complex chemotherapy of generalized drug-resistant mycobacterium tuberculosis (MBT) are presented. It is established that cycloferon (3.6 mg/kg) produces a significant therapeu... |
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[Increase of antibacterial therapy efficacy in chronic sepsis with cycloferon and reamberin combination].
Antibiot. Khimioter. 57(5-6) , 18-27, (2012) The use of reamberin and cycloferon combination for increasing the antibacterial therapy efficacy in patients with chronic sepsis (CS) was studied. It was shown that the combination provided more rapid elimination of the CS exacerbation symptoms, normalizatio... |
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[Herpetic infection in patients with psoriasis: the improvement of therapy].
Klin. Med. (Mosk.) 90(8) , 61-3, (2012) The aim of the study was to estimate the efficacy of liniment cycloferon included in combined therapy of herpetic infection in 30 patients with psoriasis divided into 2 groups. Combined treatment of patients with recurrent herpetic infection promoted eliminat... |
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[Influence of immunotropic preparation cycloferon and phytopreparations of Cynara scolimus L. on blood cytokines profile of the patients with chronic viral hepatitis C in medical rehabilitation period].
Lik. Sprava (1-2) , 102-7, (2012) The effect of the immunotropic drug cycloferon and herbal medicine resources on the basis of Cynara scolimus L. on the blood cytokine profile in the patients with chronic viral hepatitis C (CVHC) in medical rehabilitation (MR) period. Established that prior t... |
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[Cycloferon: mechanism of action, functions and application].
Eksp. Klin. Farmakol. 75(7) , 40-4, (2012) In recent years, both interferons and inductors of endogenous interferon production find increasing use in clinical practice. The latter agents are characterized by high antiviral and immunomodulatory activity in the absence of serious side effects, which mak... |
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[Clinical efficiency of reamberin - cycloferon combination in treatment of hepatic cirrhosis associated with chronic HCV infection].
Eksp. Klin. Farmakol. 75(8) , 34-8, (2012) The clinical efficiency of a reamberin and cycloferon combination for the treatment of hepatic cirrhosis (HC) associated with chronic HCV infection has been studied. Immunological investigation of patients carried out before the treatment revealed a significa... |
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[Influence of сycloferon on the сytokine blood profile and production of proinflammatory сytokines in the cultures of mononucleares of peripheral blood of the patients with chronic tonsillitis].
Vestn. Otorinolaringol. (4) , 73-6, (2012) The 88 patients with chronic tonsillitis (CT) was investigated. The 46 patients (basic group) got the modern immunoactive preparation cycloferon and 42 patients (comparison group) - only the generally accepted therapy. During immunological researches on a bac... |