(R)-(-)-1,3-Butanediol

(R)-(-)-1,3-Butanediol Structure
(R)-(-)-1,3-Butanediol structure
Common Name (R)-(-)-1,3-Butanediol
CAS Number 6290-03-5 Molecular Weight 90.121
Density 1.005 Boiling Point 207.0±0.0 °C at 760 mmHg
Molecular Formula C4H10O2 Melting Point 0ºC
MSDS Chinese USA Flash Point 108 ºC
Symbol GHS07
GHS07
Signal Word Warning

Asymmetric synthesis of (R)-1,3-butanediol from 4-hydroxy-2-butanone by a newly isolated strain Candida krusei ZJB-09162.

Appl. Microbiol. Biotechnol. 94(4) , 969-76, (2012)

Biocatalytic asymmetric preparation of (R)-1,3-butanediol has been attracting much attention in pharmaceuticals industry. A new ideal strain, ZJB-09162, which exhibited high reduction activity and excellent (R)-stereospecificity towards 4-hydroxy-2-butanone, ...

Effect of adulteration versus storage on volatiles in unifloral honeys from different floral sources and locations.

J. Food Sci. 78(2) , C184-91, (2013)

High fructose corn syrup (HFCS) was added at 5% to 40% to Indiana wildflower honey and added at 40% to Ohio and Indiana honeys from blueberry, star thistle, clover and wildflower, and an unknown source to simulate honey adulteration. Unadulterated honeys were...

Increasing analytical space in gas chromatography-differential mobility spectrometry with dispersion field amplitude programming.

J. Chromatogr. A. 1173(1-2) , 129-38, (2007)

Enhancing the analytical space of differential mobility spectrometry with dispersion field amplitude programming was proposed. Six volatile organic compound candidate breath markers, 1,3-butanediol, butanone, ethylbenzene, heptan-2-one, nonanal, and o-xylene ...

Engineering of glycerol dehydrogenase for improved activity towards 1, 3-butanediol.

Appl. Microbiol. Biotechnol. 88(1) , 117-24, (2010)

The objective of this study was to use protein engineering techniques to enhance the catalytic activity of glycerol dehydrogenase (GlyDH) on racemic 1, 3-butanediol (1, 3-BDO) for the bioproduction of the important pharmaceutical intermediate 4-hydroxy-2-buta...

Glass-forming tendency in the system water-dimethyl sulfoxide.

Cryobiology 40(2) , 151-8, (2000)

The glass-forming tendency on cooling and the stability of the wholly amorphous state on warming have been previously reported for many cryoprotective solutions. However, unlike the other solutions, those of dimethyl sulfoxide (Me(2)SO) have not been studied ...

Feasibility of cryopreservation of zebrafish (Danio rerio) primordial germ cells by whole embryo freezing.

Jpn. J. Vet. Res. 57(2) , 119-28, (2009)

We investigated the feasibility of cryopreservation of zebrafish (Danio rerio) blastomeres and primordial germ cells (PGCs) by rapid freezing of dechorionated whole embryos at the blastula, gastrula and segmentation stages. Initially we examined the glass-for...

Conformational equilibria in diols: the rotational spectrum of chiral 1,3-butandiol.

J. Phys. Chem. A 115(34) , 9585-9, (2011)

The rotational spectra of five conformers of 1,3-butandiol have been measured by pulsed jet Fourier transform microwave spectroscopy. All of them are stabilized by an internal hydrogen bond and all of them have a GG' or a G'G arrangement of the two hydroxyl o...

Novel chiral phosphoramidite monomers from (R)- and (S)-1,3-butanediol: synthesis of modified oligonucleotides and binding affinity studies.

Nucleosides Nucleotides Nucleic Acids 22(11) , 2003-11, (2003)

Two optically active phosphoramidite monomers for modified oligodeoxyribonucleotides were prepared. These monomers were then introduced into dodecanucleotides in the middle of the sequences. The modified dodecanucleotides were characterized by various analyti...

Synthesis of (R)-1,3-butanediol by enantioselective oxidation using whole recombinant Escherichia coli cells expressing (S)-specific secondary alcohol dehydrogenase.

Biosci. Biotechnol. Biochem. 66(4) , 925-7, (2002)

The synthesis of (R)-1,3-butanediol (BDO) from its racemate was studied using whole cells of recombinant Escherichia coli expressing an (S)-specific secondary alcohol dehydrogenase (CpSADH) from Candida parapsilosis by enantioselective oxidation. Under the op...

Attenuation of brain hyperbaric oxygen toxicity by fasting is not related to ketosis.

Undersea Hyperb. Med. 26(2) , 99-103, (1999)

The effect of 24 h of fasting and changes in blood glucose and beta-hydroxybutyrate (BHB) level on latency to seizures in hyperbaric oxygen (HBO2) was studied. Conscious, unrestrained rats implanted with cortical electroencephalogram electrodes were exposed t...