Glycodeoxycholate Sodium
Glycodeoxycholate Sodium structure
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Common Name | Glycodeoxycholate Sodium | ||
|---|---|---|---|---|
| CAS Number | 16409-34-0 | Molecular Weight | 472.61 | |
| Density | 0.9330g/cm3 | Boiling Point | 655.6ºC at 760 mmHg | |
| Molecular Formula | C26H43NNaO5 | Melting Point | 207 °C | |
| MSDS | Chinese USA | Flash Point | 350.3ºC | |
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Functional role of oppA encoding an oligopeptide-binding protein from Lactobacillus salivarius Ren in bile tolerance.
J. Ind. Microbiol. Biotechnol. 42 , 1167-74, (2015) Lactobacillus salivarius is a member of the indigenous microbiota of the human gastrointestinal tract (GIT), and some L. salivarius strains are considered as probiotics. Bile tolerance is a crucial property for probiotic bacteria to survive the transit throug... |
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Evaluation of cynomolgus monkeys for the identification of endogenous biomarkers for hepatic transporter inhibition and as a translatable model to predict pharmacokinetic interactions with statins in humans.
Drug Metab. Dispos. 43 , 851-63, (2015) Inhibition of hepatic transporters such as organic anion transporting polypeptides (OATPs) 1B can cause drug-drug interactions (DDIs). Determining the impact of perpetrator drugs on the plasma exposure of endogenous substrates for OATP1B could be valuable to ... |
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Mechanisms of cholesterol and saturated fatty acid lowering by Quillaja saponaria extract, studied by in vitro digestion model.
Food Funct. 6 , 1319-30, (2015) Quillaja saponin extracts are known to reduce plasma cholesterol levels in humans. Here we study the mechanism of this effect with Quillaja Dry saponin extract (QD). In vitro model of triglyceride lipolysis is used to quantify the effect of QD on the solubili... |
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Bile acids repress hypoxia-inducible factor 1 signaling and modulate the airway immune response.
Infect. Immun. 82(9) , 3531-41, (2014) Gastroesophageal reflux (GER) frequently occurs in patients with respiratory disease and is particularly prevalent in patients with cystic fibrosis. GER is a condition in which the duodenogastric contents of the stomach leak into the esophagus, in many cases ... |
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Photophysical and photodynamical study of fluoroquinolone drug molecule in bile salt aggregates.
Photochem. Photobiol. 88 , 1248, (2012) Photophysical properties of two widely used antibiotic fluoroquinolone drugs, namely Norfloxacin (NOR) and Ofloxacin (OFL) have been investigated in biomimicking environments formed by bile salts. Experimental results demonstrate that photophysical enhancemen... |
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[Study on the mechanism of Ca2+-buffering by sodium glycodeoxycholate micelles].
Guang Pu Xue Yu Guang Pu Fen Xi 30 , 748, (2010) In the present article, NaGDC was used to study the Ca(2+)-buffering capability of bile salt micelles. NaGDC is a naturally occurring bile salt which constitutes approximately 10 molar percent of bile salt composition in gallbladder. The authors selected glyc... |
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Metabolomics reveals novel biomarkers of illegal 5-nitromimidazole treatment in pigs. Further evidence of drug toxicity uncovered.
Food Chem. 199 , 876-84, (2016) The aim of the study was to investigate the potential of a metabolomics platform to distinguish between pigs treated with ronidazole, dimetridazole and metronidazole and non-medicated animals (controls), at two withdrawal periods (day 0 and 5). Livers from ea... |
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The influence of small intestinal mucus structure on particle transport ex vivo.
Colloids Surf. B Biointerfaces 135 , 73-80, (2015) Mucus provides a barrier to bacteria and toxins while allowing nutrient absorption and waste transport. Unlike colonic mucus, small intestinal mucus structure is poorly understood. This study aimed to provide evidence for a continuous, structured mucus layer ... |
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Biofilm Formation and Detachment in Gram-Negative Pathogens Is Modulated by Select Bile Acids.
PLoS ONE 11 , e0149603, (2016) Biofilms are a ubiquitous feature of microbial community structure in both natural and host environments; they enhance transmission and infectivity of pathogens and provide protection from human defense mechanisms and antibiotics. However, few natural product... |
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The protective role of the Bowman-Birk protease inhibitor in soybean lunasin digestion: the effect of released peptides on colon cancer growth.
Food Funct. 6 , 2626-35, (2015) Lunasin is a naturally-occurring peptide demonstrating chemopreventive, antioxidant and anti-inflammatory properties. To exhibit these activities, orally ingested lunasin needs to survive proteolytic attack of digestive enzymes to reach target tissues in acti... |