diethylmalonic acid
diethylmalonic acid structure
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Common Name | diethylmalonic acid | ||
|---|---|---|---|---|
| CAS Number | 510-20-3 | Molecular Weight | 160.16800 | |
| Density | 1.2g/cm3 | Boiling Point | 323.8ºC at 760mmHg | |
| Molecular Formula | C7H12O4 | Melting Point | 129-131ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 163.9ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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A modified, high yield procedure for the synthesis of unlabeled and 14C-labeled 4-methylene-DL-glutamic acid.
Prep. Biochem. 11(3) , 339-50, (1981) This paper describes the complete chemical synthesis of 4-methylene-DL-glutamic acid from diethylmalonate, formaldehyde and diethyl acetamidomalonate. The amino acid was obtained pure following ion-exchange chromatography and/or crystallization from hot water... |
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Evaluation of malonanilides as new stabilizers for double-base propellants.
J. Hazard. Mater. 73(3) , 237-44, (2000) Five malonanilide derivatives (M1-M5) were prepared by the reaction of ethyl malonate with aniline derivatives. These compounds were investigated as new stabilizers for double-base propellants (DBPs). The evaluation process has been performed through thermal ... |
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A general and mild copper-catalyzed arylation of diethyl malonate.
Org. Lett. 4(2) , 269-72, (2002) [reaction: see text] A general method for the synthesis of alpha-aryl malonates is described. The coupling of an aryl iodide and diethyl malonate in the presence of Cs(2)CO(3) and catalytic amounts of copper(I) iodide and 2-phenylphenol affords the alpha-aryl... |
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Synthesis and biological activities of novel structural analogues of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand.
Bioorg. Med. Chem. Lett. 11(15) , 1985-8, (2001) Novel analogues of 2-arachidonoylglycerol (2-AG), an endogenous cannabinoid receptor ligand, were developed. Chemical synthesis of these analogues (2-AGA105 and 2-AGA109) was accomplished starting from 2-octyn-1-ol and diethyl malonate and employing Wittig co... |
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Effect of various growth conditions on spore formation and bacillomycin L production in Bacillus subtilis.
Can. J. Microbiol. 32(3) , 254-8, (1986) Bacillomycin L is produced by Bacillus subtilis NCIB 8872 in the stationary phase; it is excreted into the culture medium, without prior accumulation in the bacterial cells. The production of bacillomycin L is largely dependent on the composition of the cultu... |
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Effects of diethylmalonate & alpha-picolinic acid on levels of inorganic nitrogen & tricarboxylic acid cycle enzymes in L-alanine utilizing B. brevis.
Indian J. Biochem. Biophys. 20(1) , 39-42, (1983)
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Synthesis and CNS activity of new 1-alkyl-2-aryl-7-hydroxy-5(1H)oxo-imidazo[1,2-a]pyrymidines.
Acta Pol. Pharm. 53(3) , 209-12, (1996) Cyclocondensation of 1,5-disubstituted 2-aminoimidazolines with diethyl malonate in the presence of sodium methanolate leading to imidazol[1,2-alpyrimidine-5,7-dion system is presented. Prevailing of 7-hydroxy-5(1H)oxo form between three possible tautomers is... |
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[The synthesis of multifunctional groups and multibranched compounds: IX. Synthesis of several branched building block].
Hua Xi Yi Ke Da Xue Xue Bao 30(1) , 37-9, (1999) The branched building plays a pivotal part in the study of Dendrimers. In order to synthesized Dendrimers more effectively, we designed and synthesized four new branched building blocks via 2-4 steps starting from diethyl malonate and pentaerythritol. Their s... |
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Development of an in vitro model for determining the fate of chemicals applied to skin.
Fundam. Appl. Toxicol. 4(2 Pt 2) , S133-44, (1984) An in vitro apparatus was developed to determine the evaporation and percutaneous penetration of radiolabeled chemicals applied to pig skin. The dermal side of the skin was mounted on a penetration cell. Appearance of radioactivity in the fluid flowing past t... |
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Evaluation of animal models for predicting skin penetration in man.
Fundam. Appl. Toxicol. 4(2 Pt 2) , S224-30, (1984) The human skin grafted athymic nude mouse, pig skin grafted athymic nude mouse, hairless dog, and weanling Yorkshire pig were evaluated as models for predicting skin penetration in man. Nine radiolabeled compounds previously tested on man were applied topical... |