4-Pyridoxic acid
4-Pyridoxic acid structure
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Common Name | 4-Pyridoxic acid | ||
|---|---|---|---|---|
| CAS Number | 82-82-6 | Molecular Weight | 183.16100 | |
| Density | 1.48g/cm3 | Boiling Point | 584.5ºC at 760 mmHg | |
| Molecular Formula | C8H9NO4 | Melting Point | 258-261ºC (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 307.3ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Automated screening of urine samples for carbohydrates, organic and amino acids after treatment with urease.
J. Chromatogr. A. 562(1-2) , 125-38, (1991) Eighty-five clinical urine samples and nineteen urine samples previously found by other laboratories to suggest genetic metabolic defects were prepared for trimethylsilylation by treatment with urease, followed by azeotropic dehydration. The "Target Analyte S... |
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Clinical analysis of vitamin B(6): determination of pyridoxal 5'-phosphate and 4-pyridoxic acid in human serum by reversed-phase high-performance liquid chromatography with chlorite postcolumn derivatization.
Anal. Biochem. 333(2) , 336-44, (2004) A reversed-phase high-performance liquid chromatography (HPLC) method with fluorometric detection was developed for the routine determination of pyridoxal 5'-phosphate (PLP) and 4-pyridoxic acid (4-PA) in serum. Chlorite postcolumn derivatization was used to ... |
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Whole Grain Consumption Increases Gastrointestinal Content of Sulfate-Conjugated Oxylipins in Pigs - A Multicompartmental Metabolomics Study.
J. Proteome Res. 14 , 3095-110, (2015) The effects of increased intake of dietary fiber as either whole grain rye or as resistant starch compared to a typical low dietary fiber Western-style diet on the metabolomics responses were studied in gastrointestinal content and tissue, peripheral plasma, ... |
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Major factors modulating the serum oxalic acid level in hemodialysis patients.
Front. Biosci. 9 , 2901-8, (2004) Ascorbic acid overload and vitamin B6 deficiency have been implicated in the development of hyperoxalemia in dialysis patients, but there is still disagreement about this. Hemodialysis patients who are exposed long-term hyperoxalemia may develop secondary oxa... |
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Vitamin B-6 vitamer levels in plasma and related symptoms in hemodialysis subjects taking low- and high-dose renal multivitamin supplements.
Int. J. Vitam. Nutr. Res. 82(2) , 130-6, (2012) The purpose of this study was to evaluate the B-6 vitamers in plasma and related symptoms in hemodialysis subjects taking high- or low-dose vitamins.A total of 24 hemodialysis (HD) subjects were divided into two groups. Twelve subjects received a high-dose vi... |
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The intestine plays a substantial role in human vitamin B6 metabolism: a Caco-2 cell model.
PLoS ONE 8(1) , e54113, (2013) Vitamin B6 is present in various forms (vitamers) in the diet that need to be metabolized to pyridoxal phosphate (PLP), the active cofactor form of vitamin B6. In literature, the liver has been reported to be the major site for this conversion, whereas the ex... |
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Inflammation causes tissue-specific depletion of vitamin B6.
Arthritis. Res. Ther. 7(6) , R1254-62, (2005) Previously we observed strong and consistent associations between vitamin B6 status and several indicators of inflammation in patients with rheumatoid arthritis. Clinical indicators, including the disability score, the length of morning stiffness, and the deg... |
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Vitamin B6 status, immune response and inflammation markers in kidney transplant recipients treated with polyclonal anti-thymocyte globulin.
Transplant. Proc. 46(8) , 2631-5, (2014) Vitamin B6 status has an impact on the body's inflammatory and immune responses. Immunosuppressive therapy may influence vitamin B6 metabolism in kidney transplant recipients. Treatment with polyclonal anti-thymocyte globulin (ATG) is associated with long-ter... |
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Untargeted metabolomics identifies enterobiome metabolites and putative uremic toxins as substrates of organic anion transporter 1 (Oat1).
J. Proteome Res. 10(6) , 2842-51, (2011) Untargeted metabolomics on the plasma and urine from wild-type and organic anion transporter-1 (Oat1/Slc22a6) knockout mice identified a number of physiologically important metabolites, including several not previously linked to Oat1-mediated transport. Sever... |
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Fate of dietary tryptophan in young Japanese women.
Int. J. Tryptophan Res. 5 , 33-47, (2012) The purpose of this study was to determine, using the high-performance liquid chromatographic methods recently modified by us, the fate of dietary tryptophan in 17 healthy female Japanese adults who ate self-selected food. The experimental period was 22 days.... |