Flumethasone

Flumethasone Structure
Flumethasone structure
Common Name Flumethasone
CAS Number 2135-17-3 Molecular Weight 410.452
Density 1.4±0.1 g/cm3 Boiling Point 569.8±50.0 °C at 760 mmHg
Molecular Formula C22H28F2O5 Melting Point 237-240ºC
MSDS Chinese USA Flash Point 298.4±30.1 °C
Symbol GHS08
GHS08
Signal Word Warning

Veterinary drug residues in domestic and imported foods of animal origin in the Republic of Korea.

Food. Addit. Contam. Part. B. Surveill. 8 , 106-12, (2015)

The Korean National Residue Programme comprises three different approaches for evaluating domestic and imported foods of animal origin: monitoring, surveillance/enforcement and an exploratory test programme. Monitoring and surveillance/enforcement testing pro...

Lecithin based nanoemulsions: A comparative study of the influence of non-ionic surfactants and the cationic phytosphingosine on physicochemical behaviour and skin permeation.

Int. J. Pharm. 370(1-2) , 181-6, (2009)

Charged drug delivery systems are interesting candidates for the delivery of drugs through skin. In the present study, it was possible to create negatively and positively charged oil/water nanoemulsions by using sucrose laureate and polysorbate 80 as non-ioni...

Tympanoplasty graft preparation using ear drops containing polyethylene glycol, flumethasone and clioquinol.

J. Laryngol. Otol. 125(8) , 853-5, (2011)

The aim of tympanoplasty graft preparation is to stiffen the fascia or perichondrium and thereby to optimise ease of manipulation. We report 39 cases utilising a novel technique in which the graft is prepared in ear drops containing polyethylene glycol, flume...

Simultaneous detection of flumethasone, dl-methylephedrine, and 2-hydroxy-4,6-dimethylpyrimidine in porcine muscle and pasteurized cow milk using liquid chromatography coupled with triple-quadrupole mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 1012-1013 , 16-Aug, (2016)

A simple analytical method based on liquid chromatography coupled with triple-quadrupole mass spectrometry was developed for detection of the veterinary drugs flumethasone, dl-methylephedrine, and 2-hydroxy-4,6-dimethylpyrimidine in porcine muscle and pasteur...

Effect of selected fluorinated drugs in a "ringing" gel on rheological behaviour and skin permeation.

Eur. J. Pharm. Biopharm. 66(1) , 120-6, (2007)

The purpose of the present study was to investigate the influence of different drugs exhibiting different solubility on the viscoelastic properties and on the skin diffusion profile of a ringing gel. In a preliminary rheology study with the placebo gel predom...

Otic drops used to clear a blocked grommet: an in vitro prospective randomized controlled study with blinded assessment.

Clin. Otolaryngol. Allied Sci. 29(6) , 602-5, (2004)

Clinicians often prescribe otic drops anecdotally to try and clear grommets blocked with blood. We carried out an in vitro double-blind randomized controlled study comparing the efficacy of sodium bicarbonate, Locorten Vioform and olive oil drops in clearing ...

Flexor carpi ulnaris tendonopathy in a Weimaraner.

Aust. Vet. J. 85(10) , 401-4, (2007)

Flumethasone-induced insulin resistance in calves.

Zentralbl. Veterinarmed. A 45(6-7) , 441-3, (1998)

The impact of one single therapeutic dose of flumethasone (0.5 mg/100 kg b.w.) on insulin sensitivity was studied in calves. Hyperinsulinemic, euglycemic clamp tests were performed before and after flumethasone treatment. At 24 h after treatment, insulin-depe...

A high-performance liquid chromatography/tandem mass spectrometric screening method for eight synthetic corticosteroids in bovine feces and the simultaneous differentiation between dexamethasone and betamethasone.

Rapid Commun. Mass Spectrom. 16(16) , 1590-4, (2002)

A screening method was developed to monitor the illegal use of synthetic corticosteroids in cattle. Diethyl ether extracts from spiked feces samples were cleaned-up by solid phase extraction followed by semipreparative reversed-phase chromatography (RPC). The...

Determination of dexamethasone and dexamethasone sodium phosphate in human plasma and cochlear perilymph by liquid chromatography/tandem mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 879(1) , 17-24, (2011)

A rapid, simple and sensitive liquid chromatography/tandem mass spectrometry (LC-MS/MS) assay was developed for the determination of dexamethasone (Dex) and dexamethasone sodium phosphate (Dex SP) in plasma and human cochlear perilymph. After proteins were pr...