Zentralblatt fur Veterinarmedizin. Reihe A 1998-09-01

Flumethasone-induced insulin resistance in calves.

K Sternbauer, J Luthman, S O Jacobsson

Index: Zentralbl. Veterinarmed. A 45(6-7) , 441-3, (1998)

Full Text: HTML

Abstract

The impact of one single therapeutic dose of flumethasone (0.5 mg/100 kg b.w.) on insulin sensitivity was studied in calves. Hyperinsulinemic, euglycemic clamp tests were performed before and after flumethasone treatment. At 24 h after treatment, insulin-dependent glucose utilization was reduced by 74% (P < 0.005). No significant changes occurred 72 h post-treatment.